Beclomethasone

Name: Beclomethasone
Brand: Vaqora Chemicals
SKU: VQ-021743

About Beclomethasone

Listed under CAS 4419-39-0, Beclomethasone is an impurity of Betamethasone available from Vaqora Chemicals. The compound has the formula C22H29ClO5, corresponding to a molecular weight of 408.9 g/mol. Alternative names: Beclometasone and BMJ 5800.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Betamethasone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Beclomethasone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Betamethasone

View every impurity, metabolite and intermediate we list for Betamethasone.

Betamethasone impurities

Specifications & identifiers

Chemical identifiers
Product name	Beclomethasone
Catalogue No.	VQ-021743
CAS Number	4419-39-0
IUPAC name	(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₂₉ClO₅
Molecular weight	408.9 g/mol
Exact mass	408.1704
Grade	Reference Standard
HSN code	38229090
InChIKey	NBMKJKDGKREAPL-DVTGEIKXSA-N
SMILES	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)Cl)C
PubChem CID	20469

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	3 / 5
TPSA	94.8 Å²
Synonyms	Beclometasone, 9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione, BMJ 5800, (11beta,16beta)-9-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, Ascocortonyl, Viarin, 9alpha-Chloro-16beta-methylprednisolone, pulvinal, 9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione (Beclometasone), Pregna-1,4-diene-3,20-dione, 9-chloro-11,17,21-trihydroxy-16-methyl-, (11.beta.,16.beta.)-, Opera_ID_1081, 9a-Chloro-16b-methylprednisolone

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P272, P280, P302 + P352, P318, P319, P321, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Beclomethasone?

The CAS Registry Number of Beclomethasone is 4419-39-0. It is also known as Beclometasone, 9-Chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione, BMJ 5800.

What is the molecular formula and molecular weight of Beclomethasone?

Beclomethasone has the molecular formula C22H29ClO5 and a molecular weight of 408.9 g/mol. Its IUPAC name is (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one.

What is Beclomethasone used for?

Beclomethasone is supplied as a characterised reference material related to Betamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Beclomethasone can I order?

We supply Beclomethasone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Beclomethasone?

Yes. Every lot of Beclomethasone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Beclomethasone be shipped internationally?

Yes. Beclomethasone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.