Bedaquiline

Name: Bedaquiline
Brand: Vaqora Chemicals
SKU: VQ-024506

About Bedaquiline

Bedaquiline (CAS 843663-66-1) is a high-purity reference standard of Bedaquiline offered by Vaqora Chemicals. The compound has the formula C32H31BrN2O2, corresponding to a molecular weight of 555.5 g/mol. Systematically, it is named (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol. Alternative names: Bedaquiline (αS,βR)-Isomer and TMC-207.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Bedaquiline, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Bedaquiline is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Bedaquiline

View every impurity, metabolite and intermediate we list for Bedaquiline.

Bedaquiline impurities

Specifications & identifiers

Chemical identifiers
Product name	Bedaquiline
Catalogue No.	VQ-024506
CAS Number	843663-66-1
IUPAC name	(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol
Molecular formula	C₃₂H₃₁BrN₂O₂
Molecular weight	555.5 g/mol
Exact mass	554.1569
Grade	Reference Standard
HSN code	38229090
InChIKey	QUIJNHUBAXPXFS-XLJNKUFUSA-N
SMILES	CN(C)CC[C@@](C1=CC=CC2=CC=CC=C21)([C@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O
PubChem CID	5388906

Physical properties
Physical form	Solid
LogP (XLogP3)	7.2
H-bond donors / acceptors	1 / 4
TPSA	45.6 Å²
Synonyms	Bedaquiline (αS,βR)-Isomer, TMC-207, TMC 207, 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol, 1-(6-bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-(3-fluorophenyl)-1-phenyl-butan-2-ol, (alphaR,betaS)-rel-Bedaquiline, (aS,bR)-Bedaquiline, (aR,bS)-rel-Bedaquiline, (alphaS,betaR)-Bedaquiline, (, AR,, AS)-rel-Bedaquiline

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P260, P264, P270, P273, P301 + P316, P319, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bedaquiline?

The CAS Registry Number of Bedaquiline is 843663-66-1. It is also known as Bedaquiline (αS,βR)-Isomer, TMC-207, TMC 207.

What is the molecular formula and molecular weight of Bedaquiline?

Bedaquiline has the molecular formula C32H31BrN2O2 and a molecular weight of 555.5 g/mol. Its IUPAC name is (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol.

What is Bedaquiline used for?

Bedaquiline is supplied as a characterised reference material related to Bedaquiline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bedaquiline can I order?

We supply Bedaquiline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bedaquiline?

Yes. Every lot of Bedaquiline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bedaquiline be shipped internationally?

Yes. Bedaquiline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.