Belzutifan

Name: Belzutifan
Brand: Vaqora Chemicals
SKU: VQ-007335

About Belzutifan

Listed under CAS 1672668-24-4, Belzutifan is a high-purity reference standard of Belzutifan available from Vaqora Chemicals. The compound has the formula C17H12F3NO4S, corresponding to a molecular weight of 383.3 g/mol. Its systematic (IUPAC) name is 3-[[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-methylsulfonyl-2,3-dihydro-1H-inden-4-yl]oxy]-5-fluorobenzonitrile. Alternative names: HIF-2alpha Inhibitor PT2977 and Welireg (TN).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Belzutifan, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Belzutifan is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Belzutifan

View every impurity, metabolite and intermediate we list for Belzutifan.

Belzutifan impurities

Specifications & identifiers

Chemical identifiers
Product name	Belzutifan
Catalogue No.	VQ-007335
CAS Number	1672668-24-4
IUPAC name	3-[[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-methylsulfonyl-2,3-dihydro-1H-inden-4-yl]oxy]-5-fluorobenzonitrile
Molecular formula	C₁₇H₁₂F₃NO₄S
Molecular weight	383.3 g/mol
Exact mass	383.0439
Grade	Reference Standard
HSN code	38229090
InChIKey	LOMMPXLFBTZENJ-ZACQAIPSSA-N
SMILES	CS(=O)(=O)C1=C2[C@@H]([C@@H]([C@@H](C2=C(C=C1)OC3=CC(=CC(=C3)C#N)F)F)F)O
PubChem CID	117947097

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 8
TPSA	95.8 Å²
Synonyms	3-((1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl)oxy-5-fluorobenzonitrile, 3-((1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl)oxy-5-fluoro-benzonitrile, HIF-2alpha Inhibitor PT2977, Welireg (TN), Belzutifan (JAN/USAN/INN), EX-A4441, US9896418, Compound 289, compound 2 [PMID: 31282155], 3-[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-methylsulfonyl-indan-4-yl]oxy-5-fluoro-benzonitrile

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P273, P280, P318, P319, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Belzutifan?

The CAS Registry Number of Belzutifan is 1672668-24-4. It is also known as 3-((1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl)oxy-5-fluorobenzonitrile, 3-((1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl)oxy-5-fluoro-benzonitrile, HIF-2alpha Inhibitor PT2977.

What is the molecular formula and molecular weight of Belzutifan?

Belzutifan has the molecular formula C17H12F3NO4S and a molecular weight of 383.3 g/mol. Its IUPAC name is 3-[[(1S,2S,3R)-2,3-difluoro-1-hydroxy-7-methylsulfonyl-2,3-dihydro-1H-inden-4-yl]oxy]-5-fluorobenzonitrile.

What is Belzutifan used for?

Belzutifan is supplied as a characterised reference material related to Belzutifan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Belzutifan can I order?

We supply Belzutifan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Belzutifan?

Yes. Every lot of Belzutifan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Belzutifan be shipped internationally?

Yes. Belzutifan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.