Bendamustine Dihydroxy Impurity

Name: Bendamustine Dihydroxy Impurity
Brand: Vaqora Chemicals
SKU: VQ-004505

About Bendamustine Dihydroxy Impurity

Bendamustine Dihydroxy Impurity (CAS 109882-30-6) is an impurity of Bendamustine offered by Vaqora Chemicals with a typical assay of 99.52%. The compound has the formula C16H23N3O4, corresponding to a molecular weight of 321.37 g/mol. Systematically, it is named 4-[5-[bis(2-hydroxyethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid. It is also known as Dihydroxy Bendamustine or Bendamustine Related Compound A (USP).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Bendamustine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bendamustine

View every impurity, metabolite and intermediate we list for Bendamustine.

Bendamustine impurities

Specifications & identifiers

Chemical identifiers
Product name	Bendamustine Dihydroxy Impurity
Catalogue No.	VQ-004505
CAS Number	109882-30-6
Other CAS	109882-29-3
IUPAC name	4-[5-[bis(2-hydroxyethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
Molecular formula	C₁₆H₂₃N₃O₄
Molecular weight	321.37 g/mol
Exact mass	321.1689
Grade	Reference Standard
Purity / assay	99.52%
HSN code	38229090
InChIKey	XQMDIDKYVZPCNV-UHFFFAOYSA-N
SMILES	CN1C2=C(C=C(C=C2)N(CCO)CCO)N=C1CCCC(=O)O
PubChem CID	13755672

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	3 / 6
TPSA	98.8 Å²
Synonyms	5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid, 4-(5-(Bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid, 4-{5-[Bis-(2-hydroxyethyl)-amino]-1-methyl-1H-benzoimidazol-2-yl}-butyric acid, Dihydroxy Bendamustine, Bendamustine Related Compound A (USP), 4-(5-(Bis(2-hydroxyethyl)amino)-1-methylbenzimidazol-2-yl)butanoic acid, Des(di(2-chloroethyl))-di(2-hydroxyethyl) bendamustine, Dihydroxy Bendamustine Sodium Salt, 1H-Benzimidazole-2-butanoic acid, 5-(bis(2-hydroxyethyl)amino)-1-methyl-, 4-{5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazol-2-yl}butanoic acid, 4-{5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-1,3-benzimidazol-2-yl}butanoic acid

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P316, P318, P319, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bendamustine Dihydroxy Impurity?

The CAS Registry Number of Bendamustine Dihydroxy Impurity is 109882-30-6. It is also known as 5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid, 4-(5-(Bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid, 4-{5-[Bis-(2-hydroxyethyl)-amino]-1-methyl-1H-benzoimidazol-2-yl}-butyric acid.

What is the molecular formula and molecular weight of Bendamustine Dihydroxy Impurity?

Bendamustine Dihydroxy Impurity has the molecular formula C16H23N3O4 and a molecular weight of 321.37 g/mol. Its IUPAC name is 4-[5-[bis(2-hydroxyethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid.

What is Bendamustine Dihydroxy Impurity used for?

Bendamustine Dihydroxy Impurity is supplied as a characterised reference material related to Bendamustine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bendamustine Dihydroxy Impurity can I order?

We supply Bendamustine Dihydroxy Impurity in Reference Standard (99.52%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bendamustine Dihydroxy Impurity?

Yes. Every lot of Bendamustine Dihydroxy Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bendamustine Dihydroxy Impurity be shipped internationally?

Yes. Bendamustine Dihydroxy Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.