Bortezomib Impurity H

Name: Bortezomib Impurity H
Brand: Vaqora Chemicals
SKU: VQ-004542

About Bortezomib Impurity H

Bortezomib Impurity H is an impurity of Bortezomib carrying the CAS registry number 1446194-56-4 at a purity of 96.27%. Formula C19H24N4O2, molecular weight 340.4 g/mol. Systematically, it is named N-[(2S)-1-(3-methylbutylamino)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide. It is also known as Bortezomib Impurity S.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Bortezomib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Bortezomib Impurity H in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bortezomib

View every impurity, metabolite and intermediate we list for Bortezomib.

Bortezomib impurities

Specifications & identifiers

Chemical identifiers
Product name	Bortezomib Impurity H
Catalogue No.	VQ-004542
CAS Number	1446194-56-4
IUPAC name	N-[(2S)-1-(3-methylbutylamino)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
Molecular formula	C₁₉H₂₄N₄O₂
Molecular weight	340.4 g/mol
Exact mass	340.1899
Grade	Reference Standard
Purity / assay	96.27%
HSN code	38229090
InChIKey	UJZOAWFAGJVEGQ-INIZCTEOSA-N
SMILES	CC(C)CCNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2
PubChem CID	68731692

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	2 / 4
TPSA	84 Å²
Synonyms	(S)-N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide, N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide, Bortezomib Impurity S, 2-Pyrazinecarboxamide, N-((1S)-2-((3-methylbutyl)amino)-2-oxo-1-(phenylmethyl)ethyl)-, N-((1S)-2-((3-Methylbutyl)amino)-2-oxo-1-(phenylmethyl)ethyl)-2-pyrazinecarboxamide, 2-Pyrazinecarboxamide, N-[(1S)-2-[(3-methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bortezomib Impurity H?

The CAS Registry Number of Bortezomib Impurity H is 1446194-56-4. It is also known as (S)-N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide, N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide, Bortezomib Impurity S.

What is the molecular formula and molecular weight of Bortezomib Impurity H?

Bortezomib Impurity H has the molecular formula C19H24N4O2 and a molecular weight of 340.4 g/mol. Its IUPAC name is N-[(2S)-1-(3-methylbutylamino)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide.

What is Bortezomib Impurity H used for?

Bortezomib Impurity H is supplied as a characterised reference material related to Bortezomib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bortezomib Impurity H can I order?

We supply Bortezomib Impurity H in Reference Standard (96.27%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bortezomib Impurity H?

Yes. Every lot of Bortezomib Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bortezomib Impurity H be shipped internationally?

Yes. Bortezomib Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.