Bosutinib Didesmethyl Impurity

Name: Bosutinib Didesmethyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-021867

About Bosutinib Didesmethyl Impurity

Listed under CAS 2468737-94-0, Bosutinib Didesmethyl Impurity is a metabolite or degradation product of Bosutinib available from Vaqora Chemicals. The compound has the formula C24H25Cl2N5O3, corresponding to a molecular weight of 502.4 g/mol. Its systematic (IUPAC) name is 4-(2,4-dichloro-5-hydroxyanilino)-6-hydroxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile. Common synonyms include 5,6-Dihydroxy-Des(dimethoxy) Bosutinib and Bosutinib Impurity 21.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Bosutinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bosutinib

View every impurity, metabolite and intermediate we list for Bosutinib.

Bosutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Bosutinib Didesmethyl Impurity
Catalogue No.	VQ-021867
CAS Number	2468737-94-0
IUPAC name	4-(2,4-dichloro-5-hydroxyanilino)-6-hydroxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
Molecular formula	C₂₄H₂₅Cl₂N₅O₃
Molecular weight	502.4 g/mol
Exact mass	501.1334
Grade	Reference Standard
HSN code	38229090
InChIKey	YATLVPNWKIGHJX-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)O)C#N)O
PubChem CID	165428991

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	3 / 8
TPSA	105 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bosutinib Didesmethyl Impurity?

The CAS Registry Number of Bosutinib Didesmethyl Impurity is 2468737-94-0. It is also known as 5,6-Dihydroxy-Des(dimethoxy) Bosutinib, Bosutinib Impurity 21.

What is the molecular formula and molecular weight of Bosutinib Didesmethyl Impurity?

Bosutinib Didesmethyl Impurity has the molecular formula C24H25Cl2N5O3 and a molecular weight of 502.4 g/mol. Its IUPAC name is 4-(2,4-dichloro-5-hydroxyanilino)-6-hydroxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile.

What is Bosutinib Didesmethyl Impurity used for?

Bosutinib Didesmethyl Impurity is supplied as a characterised reference material related to Bosutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bosutinib Didesmethyl Impurity can I order?

We supply Bosutinib Didesmethyl Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bosutinib Didesmethyl Impurity?

Yes. Every lot of Bosutinib Didesmethyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bosutinib Didesmethyl Impurity be shipped internationally?

Yes. We export Bosutinib Didesmethyl Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.