Brigatinib

Name: Brigatinib
Brand: Vaqora Chemicals
SKU: VQ-021875

About Brigatinib

Vaqora Chemicals supplies Brigatinib, a high-purity reference standard of Brigatinib registered under CAS number 1197953-54-0. Formula C29H39ClN7O2P, molecular weight 584.1 g/mol. It is also known as Brigatinib (AP-26113) or Brigatinib (AP26113).

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Brigatinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Brigatinib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Brigatinib

View every impurity, metabolite and intermediate we list for Brigatinib.

Brigatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Brigatinib
Catalogue No.	VQ-021875
CAS Number	1197953-54-0
IUPAC name	5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidine-2,4-diamine
Molecular formula	C₂₉H₃₉ClN₇O₂P
Molecular weight	584.1 g/mol
Exact mass	583.2591
Grade	Reference Standard
HSN code	38229090
InChIKey	AILRADAXUVEEIR-UHFFFAOYSA-N
SMILES	CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)NC5=CC=CC=C5P(=O)(C)C)Cl)OC
PubChem CID	68165256

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	2 / 9
TPSA	85.9 Å²
Synonyms	Brigatinib (AP-26113), Brigatinib (AP26113), 6GY, Brigatinib (JAN/USAN), EX-A775

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P316, P318, P319, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Brigatinib?

The CAS Registry Number of Brigatinib is 1197953-54-0. It is also known as Brigatinib (AP-26113), Brigatinib (AP26113), 6GY.

What is the molecular formula and molecular weight of Brigatinib?

Brigatinib has the molecular formula C29H39ClN7O2P and a molecular weight of 584.1 g/mol. Its IUPAC name is 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidine-2,4-diamine.

What is Brigatinib used for?

Brigatinib is supplied as a characterised reference material related to Brigatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Brigatinib can I order?

We supply Brigatinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Brigatinib?

Yes. Every lot of Brigatinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Brigatinib be shipped internationally?

Yes. Brigatinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.