Brinzolamide

Name: Brinzolamide
Brand: Vaqora Chemicals
SKU: VQ-021884

About Brinzolamide

Vaqora Chemicals supplies Brinzolamide, an API impurity reference standard registered under CAS number 138890-62-7. The compound has the formula C12H21N3O5S3, corresponding to a molecular weight of 383.5 g/mol. Its systematic (IUPAC) name is (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide. Common synonyms include Birnzolamide and Brinzolamide (BRZ).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of the parent drug substance, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Brinzolamide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	Brinzolamide
Catalogue No.	VQ-021884
CAS Number	138890-62-7
IUPAC name	(4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide
Molecular formula	C₁₂H₂₁N₃O₅S₃
Molecular weight	383.5 g/mol
Exact mass	383.0643
Grade	Reference Standard
HSN code	38229090
InChIKey	HCRKCZRJWPKOAR-JTQLQIEISA-N
SMILES	CCN[C@H]1CN(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)CCCOC
PubChem CID	68844

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.3
H-bond donors / acceptors	2 / 9
TPSA	164 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Brinzolamide?

The CAS Registry Number of Brinzolamide is 138890-62-7. It is also known as Birnzolamide, Brinzolamide (BRZ), 3znc.

What is the molecular formula and molecular weight of Brinzolamide?

Brinzolamide has the molecular formula C12H21N3O5S3 and a molecular weight of 383.5 g/mol. Its IUPAC name is (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide.

Which grade and pack sizes of Brinzolamide can I order?

We supply Brinzolamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Brinzolamide?

Yes. Every lot of Brinzolamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Brinzolamide be shipped internationally?

Yes. Brinzolamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.