Brivanib Alaninate

Name: Brivanib Alaninate
Brand: Vaqora Chemicals
SKU: VQ-043078

About Brivanib Alaninate

Listed under CAS 649735-63-7, Brivanib Alaninate is an impurity of Brivanib available from Vaqora Chemicals. Its molecular formula is C22H24FN5O4 and its molecular weight is 441.5 g/mol. Alternative names: alaninati brivanibum and alaninate de brivanib.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Brivanib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Brivanib Alaninate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Brivanib

View every impurity, metabolite and intermediate we list for Brivanib.

Brivanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Brivanib Alaninate
Catalogue No.	VQ-043078
CAS Number	649735-63-7
IUPAC name	[(2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-yl] (2S)-2-aminopropanoate
Molecular formula	C₂₂H₂₄FN₅O₄
Molecular weight	441.5 g/mol
Exact mass	441.1812
Grade	Reference Standard
HSN code	38229090
InChIKey	LTEJRLHKIYCEOX-OCCSQVGLSA-N
SMILES	CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)OC(=O)[C@H](C)N)C
PubChem CID	11154925

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	2 / 8
TPSA	117 Å²
Synonyms	alaninati brivanibum, alaninate de brivanib, alaninato de brivanib, Brivanib l-alanine ester, brivanib alinate, EX-A012

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P317, P318, P319, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Brivanib Alaninate?

The CAS Registry Number of Brivanib Alaninate is 649735-63-7. It is also known as alaninati brivanibum, alaninate de brivanib, alaninato de brivanib.

What is the molecular formula and molecular weight of Brivanib Alaninate?

Brivanib Alaninate has the molecular formula C22H24FN5O4 and a molecular weight of 441.5 g/mol. Its IUPAC name is [(2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-yl] (2S)-2-aminopropanoate.

What is Brivanib Alaninate used for?

Brivanib Alaninate is supplied as a characterised reference material related to Brivanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Brivanib Alaninate can I order?

We supply Brivanib Alaninate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Brivanib Alaninate?

Yes. Every lot of Brivanib Alaninate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Brivanib Alaninate be shipped internationally?

Yes. Brivanib Alaninate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.