Cabotegravir

Name: Cabotegravir
Brand: Vaqora Chemicals
SKU: VQ-007365

About Cabotegravir

Vaqora Chemicals supplies Cabotegravir, a high-purity reference standard of Cabotegravir registered under CAS number 1051375-10-0, specified at 97.55% purity. With the molecular formula C19H17F2N3O5, it has a molar mass of 405.4 g/mol. It is also known as Apretude or GSK 744.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Cabotegravir standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Cabotegravir

View every impurity, metabolite and intermediate we list for Cabotegravir.

Cabotegravir impurities

Specifications & identifiers

Chemical identifiers
Product name	Cabotegravir
Catalogue No.	VQ-007365
CAS Number	1051375-10-0
Other CAS	1051375-13-3
IUPAC name	(3R,6S)-N-[(2,4-difluorophenyl)methyl]-10-hydroxy-6-methyl-8,11-dioxo-4-oxa-1,7-diazatricyclo[7.4.0.03,7]trideca-9,12-diene-12-carboxamide
Molecular formula	C₁₉H₁₇F₂N₃O₅
Molecular weight	405.4 g/mol
Exact mass	405.1136
Grade	Reference Standard
Purity / assay	97.55%
HSN code	38229090
InChIKey	WCWSTNLSLKSJPK-LKFCYVNXSA-N
SMILES	C[C@H]1CO[C@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
PubChem CID	54713659

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	2 / 8
TPSA	99.2 Å²
Synonyms	Apretude, GSK 744, Cabotegravir and rilpivirine, Cabotegravir (GSK744, GSK1265744), Vocabria (TN), Apretude (TN), 744 LA, Cabotegravir (Standard), Cabotegravir(GSK744), Cabotegravir (JAN/USAN/INN), Cabotegravir, GSK1265744

Safety & hazard information (GHS)

Environmental hazard

Signal word: Warning

Hazard statements

H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P273, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cabotegravir?

The CAS Registry Number of Cabotegravir is 1051375-10-0. It is also known as Apretude, GSK 744, Cabotegravir and rilpivirine.

What is the molecular formula and molecular weight of Cabotegravir?

Cabotegravir has the molecular formula C19H17F2N3O5 and a molecular weight of 405.4 g/mol. Its IUPAC name is (3R,6S)-N-[(2,4-difluorophenyl)methyl]-10-hydroxy-6-methyl-8,11-dioxo-4-oxa-1,7-diazatricyclo[7.4.0.03,7]trideca-9,12-diene-12-carboxamide.

What is Cabotegravir used for?

Cabotegravir is supplied as a characterised reference material related to Cabotegravir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cabotegravir can I order?

We supply Cabotegravir in Reference Standard (97.55%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cabotegravir?

Yes. Every lot of Cabotegravir is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cabotegravir be shipped internationally?

Yes. Cabotegravir is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.