Cabozantinib Metabolite M2a

Name: Cabozantinib Metabolite M2a
Brand: Vaqora Chemicals
SKU: VQ-044243

About Cabozantinib Metabolite M2a

Vaqora Chemicals supplies Cabozantinib Metabolite M2a, a metabolite or degradation product of Cabozantinib registered under CAS number 1628530-37-9. The compound has the formula C21H18N2O9S, corresponding to a molecular weight of 474.4 g/mol. Its systematic (IUPAC) name is 1-[[4-(7-methoxy-6-sulfooxyquinolin-4-yl)oxyphenyl]carbamoyl]cyclopropane-1-carboxylic acid. Alternative names: EXEL-1644 and Cabozantinib Des-O-fluoroanile-6'-Sulfate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Cabozantinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Cabozantinib Metabolite M2a in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Cabozantinib

View every impurity, metabolite and intermediate we list for Cabozantinib.

Cabozantinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Cabozantinib Metabolite M2a
Catalogue No.	VQ-044243
CAS Number	1628530-37-9
IUPAC name	1-[[4-(7-methoxy-6-sulfooxyquinolin-4-yl)oxyphenyl]carbamoyl]cyclopropane-1-carboxylic acid
Molecular formula	C₂₁H₁₈N₂O₉S
Molecular weight	474.4 g/mol
Exact mass	474.0733
Grade	Reference Standard
HSN code	38229090
InChIKey	NGMVKHPJYUKGJR-UHFFFAOYSA-N
SMILES	COC1=CC2=NC=CC(=C2C=C1OS(=O)(=O)O)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)O
PubChem CID	86269669

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	3 / 10
TPSA	170 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cabozantinib Metabolite M2a?

The CAS Registry Number of Cabozantinib Metabolite M2a is 1628530-37-9. It is also known as EXEL-1644, Cabozantinib Des-O-fluoroanile-6'-Sulfate.

What is the molecular formula and molecular weight of Cabozantinib Metabolite M2a?

Cabozantinib Metabolite M2a has the molecular formula C21H18N2O9S and a molecular weight of 474.4 g/mol. Its IUPAC name is 1-[[4-(7-methoxy-6-sulfooxyquinolin-4-yl)oxyphenyl]carbamoyl]cyclopropane-1-carboxylic acid.

What is Cabozantinib Metabolite M2a used for?

Cabozantinib Metabolite M2a is supplied as a characterised reference material related to Cabozantinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cabozantinib Metabolite M2a can I order?

We supply Cabozantinib Metabolite M2a in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cabozantinib Metabolite M2a?

Yes. Every lot of Cabozantinib Metabolite M2a is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cabozantinib Metabolite M2a be shipped internationally?

Yes. We export Cabozantinib Metabolite M2a worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.