Calicheamicin

Name: Calicheamicin
Brand: Vaqora Chemicals
SKU: VQ-047668

About Calicheamicin

Calicheamicin (CAS 108212-75-5) is an API reference standard offered by Vaqora Chemicals. The compound has the formula C55H74IN3O21S4, corresponding to a molecular weight of 1368.4 g/mol. Common synonyms include calicheamicin gamma(1)I and Calicheamicin gamma1I.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this the parent drug substance standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Calicheamicin in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Specifications & identifiers

Chemical identifiers
Product name	Calicheamicin
Catalogue No.	VQ-047668
CAS Number	108212-75-5
IUPAC name	S-[(2R,3S,4S,6S)-6-[[(2R,3S,4S,5R,6R)-5-[(2S,4S,5S)-5-(ethylamino)-4-methoxyoxan-2-yl]oxy-4-hydroxy-6-[[(2S,5Z,9R,13E)-9-hydroxy-12-(methoxycarbonylamino)-13-[2-(methyltrisulfanyl)ethylidene]-11-oxo-2-bicyclo[7.3.1]trideca-1(12),5-dien-3,7-diynyl]oxy]-2-methyloxan-3-yl]amino]oxy-4-hydroxy-2-methyloxan-3-yl] 4-[(2S,3R,4R,5S,6S)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5-iodo-2,3-dimethoxy-6-methylbenzenecarbothioate
Molecular formula	C₅₅H₇₄IN₃O₂₁S₄
Molecular weight	1368.4 g/mol
Exact mass	1367.2742
Grade	Reference Standard
HSN code	38229090
InChIKey	HXCHCVDVKSCDHU-PJKCJEBCSA-N
SMILES	CCN[C@H]1CO[C@H](C[C@@H]1OC)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2O[C@H]3C#C/C=C\C#C[C@@]\4(CC(=O)C(=C3/C4=C\CSSSC)NC(=O)OC)O)C)NO[C@H]5C[C@@H]([C@@H]([C@H](O5)C)SC(=O)C6=C(C(=C(C(=C6OC)OC)O[C@H]7[C@@H]([C@@H]([C@H]([C@@H](O7)C)O)OC)O)I)C)O)O
PubChem CID	10953353

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	8 / 27
TPSA	410 Å²
Synonyms	calicheamicin gamma(1)I, Calicheamicin gamma1I, Calichemicin gamma1, Calicheamicin gamma(1,I), calicheamicin gamma1(I), calicheamicin gamma1, Calicheamicin I(3)1I

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P317, P318, P319, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Calicheamicin?

The CAS Registry Number of Calicheamicin is 108212-75-5. It is also known as calicheamicin gamma(1)I, Calicheamicin gamma1I, Calichemicin gamma1.

What is the molecular formula and molecular weight of Calicheamicin?

Calicheamicin has the molecular formula C55H74IN3O21S4 and a molecular weight of 1368.4 g/mol.

Which grade and pack sizes of Calicheamicin can I order?

We supply Calicheamicin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Calicheamicin?

Yes. Every lot of Calicheamicin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Calicheamicin be shipped internationally?

Yes. Calicheamicin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.