Canagliflozin Hemihydrate

Name: Canagliflozin Hemihydrate
Brand: Vaqora Chemicals
SKU: VQ-007367

About Canagliflozin Hemihydrate

Vaqora Chemicals supplies Canagliflozin Hemihydrate, a high-purity reference standard of Canagliflozin registered under CAS number 928672-86-0. Formula C24H25FO5S, molecular weight 444.5 g/mol. It is also known as Cagliflozin hydrate or Canagliflozin.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Canagliflozin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Canagliflozin

View every impurity, metabolite and intermediate we list for Canagliflozin.

Canagliflozin impurities

Specifications & identifiers

Chemical identifiers
Product name	Canagliflozin Hemihydrate
Catalogue No.	VQ-007367
CAS Number	928672-86-0
IUPAC name	(2S,3R,4R,5S,6R)-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
Molecular formula	C₂₄H₂₅FO₅S
Molecular weight	444.5 g/mol
Exact mass	444.1407
Grade	Reference Standard
HSN code	38229090
InChIKey	XTNGUQKDFGDXSJ-ZXGKGEBGSA-N
SMILES	CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F
PubChem CID	24812758

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	4 / 7
TPSA	118 Å²
Synonyms	Cagliflozin hydrate, Canagliflozin, Canagliflozin anhydrous, 1-(Glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienylmethyl)benzene, Canagliflozine, (1S)-1,5-Anhydro-1-(3-((5-(4-fluorophenyl)-2-thienyl)methyl)-4-methylphenyl)-D-glucitol, (1S)-1,5-anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol, Canagliflozin, Anhydrous, 1-(Glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienylmethyl)benzene-T777973, (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol, Canagliflozin (Standard), (1S)-1,5-anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methyl-phenyl)-D-glucitol

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H318Causes serious eye damage
H319Causes serious eye irritation
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P263, P264, P264 + P265, P270, P273, P280, P301 + P317, P305 + P351 + P338, P305 + P354 + P338, P317, P318, P330, P337 + P317, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Canagliflozin Hemihydrate?

The CAS Registry Number of Canagliflozin Hemihydrate is 928672-86-0. It is also known as Cagliflozin hydrate, Canagliflozin, Canagliflozin anhydrous.

What is the molecular formula and molecular weight of Canagliflozin Hemihydrate?

Canagliflozin Hemihydrate has the molecular formula C24H25FO5S and a molecular weight of 444.5 g/mol. Its IUPAC name is (2S,3R,4R,5S,6R)-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]-6-(hydroxymethyl)oxane-3,4,5-triol.

What is Canagliflozin Hemihydrate used for?

Canagliflozin Hemihydrate is supplied as a characterised reference material related to Canagliflozin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Canagliflozin Hemihydrate can I order?

We supply Canagliflozin Hemihydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Canagliflozin Hemihydrate?

Yes. Every lot of Canagliflozin Hemihydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Canagliflozin Hemihydrate be shipped internationally?

Yes. Canagliflozin Hemihydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.