Ceritinib

Name: Ceritinib
Brand: Vaqora Chemicals
SKU: VQ-024910

About Ceritinib

Ceritinib (CAS 1032900-25-6) is a high-purity reference standard of Ceritinib offered by Vaqora Chemicals. With the molecular formula C28H36ClN5O3S, it has a molar mass of 558.1 g/mol. Common synonyms include LDK-378 and LDK 378.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Ceritinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ceritinib

View every impurity, metabolite and intermediate we list for Ceritinib.

Ceritinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ceritinib
Catalogue No.	VQ-024910
CAS Number	1032900-25-6
IUPAC name	5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine
Molecular formula	C₂₈H₃₆ClN₅O₃S
Molecular weight	558.1 g/mol
Exact mass	557.2227
Grade	Reference Standard
HSN code	38229090
InChIKey	VERWOWGGCGHDQE-UHFFFAOYSA-N
SMILES	CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl
PubChem CID	57379345

Physical properties
Physical form	Solid
LogP (XLogP3)	6.4
H-bond donors / acceptors	3 / 8
TPSA	114 Å²
Synonyms	LDK-378, LDK 378, Ceritinib (LDK378), 4MK, Ceritinib(LDK378), LDK378(Ceritinib), Eritinib (LDK378), CPD 15, EX-A187

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P317, P318, P319, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ceritinib?

The CAS Registry Number of Ceritinib is 1032900-25-6. It is also known as LDK-378, LDK 378, Ceritinib (LDK378).

What is the molecular formula and molecular weight of Ceritinib?

Ceritinib has the molecular formula C28H36ClN5O3S and a molecular weight of 558.1 g/mol. Its IUPAC name is 5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine.

What is Ceritinib used for?

Ceritinib is supplied as a characterised reference material related to Ceritinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ceritinib can I order?

We supply Ceritinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ceritinib?

Yes. Every lot of Ceritinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ceritinib be shipped internationally?

Yes. Ceritinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.