Cetirizine Impurity E (Dihydrochloride)

Name: Cetirizine Impurity E (Dihydrochloride)
Brand: Vaqora Chemicals
SKU: VQ-004631

About Cetirizine Impurity E (Dihydrochloride)

Listed under CAS 83881-56-5, Cetirizine Impurity E (Dihydrochloride) is an impurity of Cetirizine available from Vaqora Chemicals. With the molecular formula C23H31Cl3N2O4, it has a molar mass of 505.9 g/mol. The IUPAC name is 2-[2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethoxy]acetic acid. Dihydrochloride. It is also known as Hydroxyzine Acetic Acid Dihydrochloride or Cetirizine Imp. E (EP).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Cetirizine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cetirizine

View every impurity, metabolite and intermediate we list for Cetirizine.

Cetirizine impurities

Specifications & identifiers

Chemical identifiers
Product name	Cetirizine Impurity E (Dihydrochloride)
Catalogue No.	VQ-004631
CAS Number	83881-56-5
IUPAC name	2-[2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethoxy]acetic acid;dihydrochloride
Molecular formula	C₂₃H₃₁Cl₃N₂O₄
Molecular weight	505.9 g/mol
Exact mass	504.1349
Grade	Reference Standard
HSN code	38229090
InChIKey	ZLLSILIWIOEGTJ-UHFFFAOYSA-N
SMILES	C1CN(CCN1CCOCCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
PubChem CID	3068853

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 6
TPSA	62.2 Å²
Synonyms	Hydroxyzine Acetic Acid Dihydrochloride, Cetirizine Imp. E (EP), 682323-77-9(free base), Cetirizine EP Impurity E(Dihydrochloride), Cetirizine EP Impurity E, USP Ethoxycetirizine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cetirizine Impurity E (Dihydrochloride)?

The CAS Registry Number of Cetirizine Impurity E (Dihydrochloride) is 83881-56-5. It is also known as Hydroxyzine Acetic Acid Dihydrochloride, Cetirizine Imp. E (EP), 682323-77-9(free base).

What is the molecular formula and molecular weight of Cetirizine Impurity E (Dihydrochloride)?

Cetirizine Impurity E (Dihydrochloride) has the molecular formula C23H31Cl3N2O4 and a molecular weight of 505.9 g/mol.

What is Cetirizine Impurity E (Dihydrochloride) used for?

Cetirizine Impurity E (Dihydrochloride) is supplied as a characterised reference material related to Cetirizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cetirizine Impurity E (Dihydrochloride) can I order?

We supply Cetirizine Impurity E (Dihydrochloride) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cetirizine Impurity E (Dihydrochloride)?

Yes. Every lot of Cetirizine Impurity E (Dihydrochloride) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cetirizine Impurity E (Dihydrochloride) be shipped internationally?

Yes. Cetirizine Impurity E (Dihydrochloride) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.