Chlorambucil

Name: Chlorambucil
Brand: Vaqora Chemicals
SKU: VQ-007384

About Chlorambucil

Chlorambucil is a high-purity reference standard of Chlorambucil carrying the CAS registry number 305-03-3. With the molecular formula C14H19Cl2NO2, it has a molar mass of 304.2 g/mol. Its systematic (IUPAC) name is 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid. It is also known as Ambochlorin or Amboclorin.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Chlorambucil standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Chlorambucil

View every impurity, metabolite and intermediate we list for Chlorambucil.

Chlorambucil impurities

Specifications & identifiers

Chemical identifiers
Product name	Chlorambucil
Catalogue No.	VQ-007384
CAS Number	305-03-3
Other CAS	1030-06-4, 107602-00-6, 3308-26-7
IUPAC name	4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid
Molecular formula	C₁₄H₁₉Cl₂NO₂
Molecular weight	304.2 g/mol
Exact mass	303.0793
Grade	Reference Standard
HSN code	38229090
InChIKey	JCKYGMPEJWAADB-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1CCCC(=O)O)N(CCCl)CCCl
PubChem CID	2708

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	1 / 3
TPSA	40.5 Å²
Synonyms	4-[Bis(2-chloroethyl)amino]benzenebutanoic acid, 4-(4-(bis(2-chloroethyl)amino)phenyl)butanoic acid, 4-[p-[Bis(2-chloroethyl)amino]phenyl]butyric acid, Ambochlorin, Amboclorin, Chlorobutine, Ecloril, Leukeran, Linfolizin, Linfolysin, Lympholysin, γ-[p-Bis(2-chloroethyl)aminophenyl]butyric acid

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Chlorambucil?

The CAS Registry Number of Chlorambucil is 305-03-3. It is also known as 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid, 4-(4-(bis(2-chloroethyl)amino)phenyl)butanoic acid, 4-[p-[Bis(2-chloroethyl)amino]phenyl]butyric acid.

What is the molecular formula and molecular weight of Chlorambucil?

Chlorambucil has the molecular formula C14H19Cl2NO2 and a molecular weight of 304.2 g/mol. Its IUPAC name is 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoic acid.

What is Chlorambucil used for?

Chlorambucil is supplied as a characterised reference material related to Chlorambucil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Chlorambucil can I order?

We supply Chlorambucil in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Chlorambucil?

Yes. Every lot of Chlorambucil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Chlorambucil be shipped internationally?

Yes. Chlorambucil is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.