Chlorobis-(4-fluorophenyl)methane

Name: Chlorobis-(4-fluorophenyl)methane
Brand: Vaqora Chemicals
SKU: VQ-048413

About Chlorobis-(4-fluorophenyl)methane

Vaqora Chemicals supplies Chlorobis-(4-fluorophenyl)methane, a process intermediate or related compound of Flunarizine registered under CAS number 27064-94-4. The compound has the formula C13H9ClF2, corresponding to a molecular weight of 238.66 g/mol. Its systematic (IUPAC) name is 1-[chloro-(4-fluorophenyl)methyl]-4-fluorobenzene. Common synonyms include 4,4'-Difluorobenzhydryl chloride and 1,1'-(Chloromethylene)bis(4-fluorobenzene).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Flunarizine, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Chlorobis-(4-fluorophenyl)methane is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Flunarizine

View every impurity, metabolite and intermediate we list for Flunarizine.

Flunarizine impurities

Specifications & identifiers

Chemical identifiers
Product name	Chlorobis-(4-fluorophenyl)methane
Catalogue No.	VQ-048413
CAS Number	27064-94-4
IUPAC name	1-[chloro-(4-fluorophenyl)methyl]-4-fluorobenzene
Molecular formula	C₁₃H₉ClF₂
Molecular weight	238.66 g/mol
Exact mass	238.0361
InChIKey	FHPNLCLHMNPLEW-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(C2=CC=C(C=C2)F)Cl)F
PubChem CID	2723773

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	0 / 2
TPSA	0 Å²
Synonyms	4,4'-Difluorobenzhydryl chloride, 1,1'-(Chloromethylene)bis(4-fluorobenzene), bis(4-fluorophenyl)methyl chloride, bis(p-fluorophenyl)methyl chloride, 1,1'-(chloromethylene)bis[4-fluorobenzene], 4,4'-(Chloromethylene)bis(fluorobenzene), 4,4-Difluorodiphenylmethylchloride, 4,4'-difluorodiphenylmethylchloride, 1-[chloro(4-fluorophenyl)methyl]-4-fluorobenzene, bis-(4-fluorophenyl)methyl chloride

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P264 + P265, P271, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P319, P321, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Chlorobis-(4-fluorophenyl)methane?

The CAS Registry Number of Chlorobis-(4-fluorophenyl)methane is 27064-94-4. It is also known as 4,4'-Difluorobenzhydryl chloride, 1,1'-(Chloromethylene)bis(4-fluorobenzene), bis(4-fluorophenyl)methyl chloride.

What is the molecular formula and molecular weight of Chlorobis-(4-fluorophenyl)methane?

Chlorobis-(4-fluorophenyl)methane has the molecular formula C13H9ClF2 and a molecular weight of 238.66 g/mol. Its IUPAC name is 1-[chloro-(4-fluorophenyl)methyl]-4-fluorobenzene.

What is Chlorobis-(4-fluorophenyl)methane used for?

Chlorobis-(4-fluorophenyl)methane is supplied as a characterised reference material related to Flunarizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Chlorobis-(4-fluorophenyl)methane can I order?

We supply Chlorobis-(4-fluorophenyl)methane, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Chlorobis-(4-fluorophenyl)methane?

Yes. Every lot of Chlorobis-(4-fluorophenyl)methane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Chlorobis-(4-fluorophenyl)methane be shipped internationally?

Yes. Chlorobis-(4-fluorophenyl)methane is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.