Cilastatin

Name: Cilastatin
Brand: Vaqora Chemicals
SKU: VQ-022173

About Cilastatin

Listed under CAS 82009-34-5, Cilastatin is a high-purity reference standard of Cilastatin available from Vaqora Chemicals. Its molecular formula is C16H26N2O5S and its molecular weight is 358.5 g/mol. The IUPAC name is (Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid. Common synonyms include Cilastatin acid and Cilastatine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Cilastatin standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cilastatin in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Cilastatin

View every impurity, metabolite and intermediate we list for Cilastatin.

Cilastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	Cilastatin
Catalogue No.	VQ-022173
CAS Number	82009-34-5
IUPAC name	(Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid
Molecular formula	C₁₆H₂₆N₂O₅S
Molecular weight	358.5 g/mol
Exact mass	358.1562
Grade	Reference Standard
HSN code	38229090
InChIKey	DHSUYTOATWAVLW-WFVMDLQDSA-N
SMILES	CC1(C[C@@H]1C(=O)N/C(=C\CCCCSC[C@@H](C(=O)O)N)/C(=O)O)C
PubChem CID	6435415

Physical properties
Physical form	Solid
LogP (XLogP3)	-1
H-bond donors / acceptors	4 / 7
TPSA	155 Å²
Synonyms	Cilastatin acid, Cilastatine, MK-791, (Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine, (Z)-(S)-6-Carboxy-6-((S)-2,2-dimethylcyclopropanecarboxamido)hex-5-enyl-L-cysteine, Cilastin, MK 791, Cilastastin, EX-A4954

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cilastatin?

The CAS Registry Number of Cilastatin is 82009-34-5. It is also known as Cilastatin acid, Cilastatine, MK-791.

What is the molecular formula and molecular weight of Cilastatin?

Cilastatin has the molecular formula C16H26N2O5S and a molecular weight of 358.5 g/mol. Its IUPAC name is (Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid.

What is Cilastatin used for?

Cilastatin is supplied as a characterised reference material related to Cilastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cilastatin can I order?

We supply Cilastatin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cilastatin?

Yes. Every lot of Cilastatin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cilastatin be shipped internationally?

Yes. Cilastatin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.