Citalopram Carboxylic Acid Impurity

Name: Citalopram Carboxylic Acid Impurity
Brand: Vaqora Chemicals
SKU: VQ-004651

About Citalopram Carboxylic Acid Impurity

Listed under CAS 440121-09-5, Citalopram Carboxylic Acid Impurity is an impurity of Citalopram available from Vaqora Chemicals with a typical assay of 99.42%. With the molecular formula C20H22FNO3, it has a molar mass of 343.4 g/mol. Its systematic (IUPAC) name is 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carboxylic acid. It is also known as Citalopram Carboxylic Acid or Carboxy Citalopram.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Citalopram to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Citalopram Carboxylic Acid Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Citalopram

View every impurity, metabolite and intermediate we list for Citalopram.

Citalopram impurities

Specifications & identifiers

Chemical identifiers
Product name	Citalopram Carboxylic Acid Impurity
Catalogue No.	VQ-004651
CAS Number	440121-09-5
IUPAC name	1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carboxylic acid
Molecular formula	C₂₀H₂₂FNO₃
Molecular weight	343.4 g/mol
Exact mass	343.1584
Grade	Reference Standard
Purity / assay	99.42%
HSN code	38229090
InChIKey	GECQEQCYCDJXJC-UHFFFAOYSA-N
SMILES	CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C(=O)O)C3=CC=C(C=C3)F
PubChem CID	9928044

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	1 / 5
TPSA	49.8 Å²
Synonyms	1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carboxylic Acid, 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarboxylic acid, Citalopram Carboxylic Acid, Carboxy Citalopram, Escitalopram EP Impurity M, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-5-Isobenzofurancarboxylic acid, Citalopram EP Impurity M, Descyano citalopram carboxylic acid, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carboxylic acid, 5-Carboxy-1-(4-fluorophenyl)-1-(3-dimethylaminopropyl)-1,3-dihydro-isobenzofuran

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H335May cause respiratory irritation
H336May cause drowsiness or dizziness
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P270, P271, P273, P301 + P317, P304 + P340, P319, P330, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Citalopram Carboxylic Acid Impurity?

The CAS Registry Number of Citalopram Carboxylic Acid Impurity is 440121-09-5. It is also known as 1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carboxylic Acid, 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarboxylic acid, Citalopram Carboxylic Acid.

What is the molecular formula and molecular weight of Citalopram Carboxylic Acid Impurity?

Citalopram Carboxylic Acid Impurity has the molecular formula C20H22FNO3 and a molecular weight of 343.4 g/mol. Its IUPAC name is 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carboxylic acid.

What is Citalopram Carboxylic Acid Impurity used for?

Citalopram Carboxylic Acid Impurity is supplied as a characterised reference material related to Citalopram. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Citalopram Carboxylic Acid Impurity can I order?

We supply Citalopram Carboxylic Acid Impurity in Reference Standard (99.42%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Citalopram Carboxylic Acid Impurity?

Yes. Every lot of Citalopram Carboxylic Acid Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Citalopram Carboxylic Acid Impurity be shipped internationally?

Yes. Citalopram Carboxylic Acid Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.