Cobicistat Intermediate A

Name: Cobicistat Intermediate A
Brand: Vaqora Chemicals
SKU: VQ-013304

About Cobicistat Intermediate A

Cobicistat Intermediate A (CAS 1004316-18-0) is a process intermediate or related compound of Cobicistat offered by Vaqora Chemicals at a purity of 99.4%. The compound has the formula C23H27N3O2S, corresponding to a molecular weight of 409.5 g/mol. The IUPAC name is 1,3-thiazol-5-ylmethyl N-[(2R,5R)-5-amino-1,6-diphenylhexan-2-yl]carbamate.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is a process intermediate or related compound in the synthesis of Cobicistat, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cobicistat Intermediate A is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Cobicistat

View every impurity, metabolite and intermediate we list for Cobicistat.

Cobicistat impurities

Specifications & identifiers

Chemical identifiers
Product name	Cobicistat Intermediate A
Catalogue No.	VQ-013304
CAS Number	1004316-18-0
Other CAS	1247119-33-0, 1643376-45-7
IUPAC name	1,3-thiazol-5-ylmethyl N-[(2R,5R)-5-amino-1,6-diphenylhexan-2-yl]carbamate
Molecular formula	C₂₃H₂₇N₃O₂S
Molecular weight	409.5 g/mol
Exact mass	409.1824
Grade	Reference Standard
Purity / assay	99.4%
HSN code	2933
InChIKey	NDRGYGLCIPEVCJ-NHCUHLMSSA-N
SMILES	C1=CC=C(C=C1)C[C@@H](CC[C@H](CC2=CC=CC=C2)NC(=O)OCC3=CN=CS3)N
PubChem CID	59721242

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	2 / 5
TPSA	105 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cobicistat Intermediate A?

The CAS Registry Number of Cobicistat Intermediate A is 1004316-18-0. It is also known as 5-Thiazolylmethyl N-[(1R,4R)-4-amino-5-phenyl-1-(phenylmethyl)pentyl]carbamate, Thiazol-5-ylmethyl ((2R,5R)-5-amino-1,6-diphenylhexan-2-yl)carbamate, 5-Thiazolylmethyl N-((1R,4R)-4-amino-5-phenyl-1-(phenylmethyl)pentyl)carbamate.

What is the molecular formula and molecular weight of Cobicistat Intermediate A?

Cobicistat Intermediate A has the molecular formula C23H27N3O2S and a molecular weight of 409.5 g/mol. Its IUPAC name is 1,3-thiazol-5-ylmethyl N-[(2R,5R)-5-amino-1,6-diphenylhexan-2-yl]carbamate.

What is Cobicistat Intermediate A used for?

Cobicistat Intermediate A is supplied as a characterised reference material related to Cobicistat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cobicistat Intermediate A can I order?

We supply Cobicistat Intermediate A in Reference Standard (99.4%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cobicistat Intermediate A?

Yes. Every lot of Cobicistat Intermediate A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cobicistat Intermediate A be shipped internationally?

Yes. We export Cobicistat Intermediate A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.