Cobimetinib Fumarate

Name: Cobimetinib Fumarate
Brand: Vaqora Chemicals
SKU: VQ-036435

About Cobimetinib Fumarate

Vaqora Chemicals supplies Cobimetinib Fumarate, a high-purity reference standard of Cobimetinib registered under CAS number 1369665-02-0. The compound has the formula C46H46F6I2N6O8, corresponding to a molecular weight of 1178.7 g/mol. It is also known as Cobimetinib hemifumarate or Xl-518 hemifumarate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a reference sample of Cobimetinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cobimetinib Fumarate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Cobimetinib

View every impurity, metabolite and intermediate we list for Cobimetinib.

Cobimetinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Cobimetinib Fumarate
Catalogue No.	VQ-036435
CAS Number	1369665-02-0
IUPAC name	(E)-but-2-enedioic acid;bis([3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone)
Molecular formula	C₄₆H₄₆F₆I₂N₆O₈
Molecular weight	1178.7 g/mol
Exact mass	1178.1371
Grade	Reference Standard
HSN code	38229090
InChIKey	RESIMIUSNACMNW-BXRWSSRYSA-N
SMILES	C1CCN[C@@H](C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O.C1CCN[C@@H](C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O.C(=C/C(=O)O)\C(=O)O
PubChem CID	71491931

Physical properties
Physical form	Solid
H-bond donors / acceptors	8 / 18
TPSA	204 Å²
Synonyms	Cobimetinib hemifumarate, Xl-518 hemifumarate, GDC-0973 hemifumarate, Cobimetinib fumarate (USAN), Cobimetinib fumarate - Bio-X

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cobimetinib Fumarate?

The CAS Registry Number of Cobimetinib Fumarate is 1369665-02-0. It is also known as Cobimetinib hemifumarate, Xl-518 hemifumarate, GDC-0973 hemifumarate.

What is the molecular formula and molecular weight of Cobimetinib Fumarate?

Cobimetinib Fumarate has the molecular formula C46H46F6I2N6O8 and a molecular weight of 1178.7 g/mol.

What is Cobimetinib Fumarate used for?

Cobimetinib Fumarate is supplied as a characterised reference material related to Cobimetinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cobimetinib Fumarate can I order?

We supply Cobimetinib Fumarate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cobimetinib Fumarate?

Yes. Every lot of Cobimetinib Fumarate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cobimetinib Fumarate be shipped internationally?

Yes. We export Cobimetinib Fumarate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.