Colistimethate sodium

Name: Colistimethate sodium
Brand: Vaqora Chemicals
SKU: VQ-043460

About Colistimethate sodium

Colistimethate sodium is an API impurity reference standard carrying the CAS registry number 8068-28-8. The compound has the formula C45H85N13O10, corresponding to a molecular weight of 968.2 g/mol. It is also known as colistin methane sulfonate or Colimycine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of the parent drug substance, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Colistimethate sodium in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	Colistimethate sodium
Catalogue No.	VQ-043460
CAS Number	8068-28-8
IUPAC name	6-methyl-N-[2-[(2S,5S,8S,11S,14S,17S,20S,23S)-8,11,14,20-tetrakis(2-aminoethyl)-5-[(1R)-1-hydroxyethyl]-17,23-bis(2-methylpropyl)-3,6,9,12,15,18,21,24-octaoxo-1,4,7,10,13,16,19,22-octazacyclotetracos-2-yl]ethyl]octanamide
Molecular formula	C₄₅H₈₅N₁₃O₁₀
Molecular weight	968.2 g/mol
Exact mass	967.6542
Grade	Reference Standard
HSN code	38229090
InChIKey	RPABDKTXMKOGKI-OYTUFZPASA-N
SMILES	CCC(C)CCCCC(=O)NCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CC(C)C)CCN)CC(C)C)CCN)CCN)CCN)[C@@H](C)O
PubChem CID	44585614

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.7
H-bond donors / acceptors	14 / 14
TPSA	386 Å²
Synonyms	colistin methane sulfonate, Colimycine, Methacolimycin, Alficetin, sodio colistimetato, colistimethate sodique, colistimetato de sodio, colistimethatum natricum, First Guard Sterile Powder, Colimycin

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P263, P264, P270, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Colistimethate sodium?

The CAS Registry Number of Colistimethate sodium is 8068-28-8. It is also known as colistin methane sulfonate, Colimycine, Methacolimycin.

What is the molecular formula and molecular weight of Colistimethate sodium?

Colistimethate sodium has the molecular formula C45H85N13O10 and a molecular weight of 968.2 g/mol.

Which grade and pack sizes of Colistimethate sodium can I order?

We supply Colistimethate sodium in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Colistimethate sodium?

Yes. Every lot of Colistimethate sodium is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Colistimethate sodium be shipped internationally?

Yes. Colistimethate sodium is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.