Cyclo(L-Pro-L-Trp)

Name: Cyclo(L-Pro-L-Trp)
Brand: Vaqora Chemicals
SKU: VQ-037039

About Cyclo(L-Pro-L-Trp)

Cyclo(L-Pro-L-Trp) (CAS 38136-70-8) is an impurity of Eptifibatide offered by Vaqora Chemicals. The compound has the formula C16H17N3O2, corresponding to a molecular weight of 283.32 g/mol. The IUPAC name is (3S,8aS)-3-(1H-indol-3-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione. Alternative names: Brevianamide F and L-prolyl-L-tryptophan anhydride.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Eptifibatide, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Cyclo(L-Pro-L-Trp) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Eptifibatide

View every impurity, metabolite and intermediate we list for Eptifibatide.

Eptifibatide impurities

Specifications & identifiers

Chemical identifiers
Product name	Cyclo(L-Pro-L-Trp)
Catalogue No.	VQ-037039
CAS Number	38136-70-8
IUPAC name	(3S,8aS)-3-(1H-indol-3-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Molecular formula	C₁₆H₁₇N₃O₂
Molecular weight	283.32 g/mol
Exact mass	283.1321
Grade	Reference Standard
HSN code	38229090
InChIKey	RYFZBPVMVYTEKZ-KBPBESRZSA-N
SMILES	C1C[C@H]2C(=O)N[C@H](C(=O)N2C1)CC3=CNC4=CC=CC=C43
PubChem CID	181567

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	2 / 2
TPSA	65.2 Å²
Synonyms	Brevianamide F, L-prolyl-L-tryptophan anhydride, Cyclo-L-Trp-L-Pro, (3s,8as)-3-(1h-Indol-3-Ylmethyl)hexahydropyrrolo[1,2-A]pyrazine-1,4-Dione, (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo(1,2-a)pyrazine-1,4-dione, (3S,8aS)-3-(1H-indol-3-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo(1,2-a)pyrazine-1,4-dione, cyclo-(Trp-Pro), (3S,8aS)-3-((1H-Indol-3-yl)methyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, L-tryptophyl-L-proline cyclic anhydride, cyclo-L-proline-L-pryptophan, cyclo-L-tryptophanyl-L-proline, tryptophan-proline diketopiperazine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cyclo(L-Pro-L-Trp)?

The CAS Registry Number of Cyclo(L-Pro-L-Trp) is 38136-70-8. It is also known as Brevianamide F, L-prolyl-L-tryptophan anhydride, Cyclo-L-Trp-L-Pro.

What is the molecular formula and molecular weight of Cyclo(L-Pro-L-Trp)?

Cyclo(L-Pro-L-Trp) has the molecular formula C16H17N3O2 and a molecular weight of 283.32 g/mol. Its IUPAC name is (3S,8aS)-3-(1H-indol-3-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione.

What is Cyclo(L-Pro-L-Trp) used for?

Cyclo(L-Pro-L-Trp) is supplied as a characterised reference material related to Eptifibatide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cyclo(L-Pro-L-Trp) can I order?

We supply Cyclo(L-Pro-L-Trp) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cyclo(L-Pro-L-Trp)?

Yes. Every lot of Cyclo(L-Pro-L-Trp) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cyclo(L-Pro-L-Trp) be shipped internationally?

Yes. We export Cyclo(L-Pro-L-Trp) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.