Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine)

Name: Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine)
Brand: Vaqora Chemicals
SKU: VQ-036478

Synonyms: Cyclosporin AM 9 · (4-Hydroxy-N-methyl-L-leucine)cyclosporine · [.gamma.-Hydroxy-MeLeu]9-CsA · [.gamma.-Hydroxy-MeLeu]9-Ciclosporin

CAS No.89270-25-7

FormulaC₆₂H₁₁₁N₁₁O₁₃

Mol. weight1,218.60

Catalogue No.VQ-036478

PurityReference Standard

HSN38229090

Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) (CAS 89270-25-7) – Cyclosporin impurity standard. C62H111N11O13, MW 1218.6. With COA, ships worldwide.

Pack sizesPrice on quotation · bulk available

10 mg

25 mg

50 mg

100 mg

Bulk / custom pack · kg to MT

Enquire

Batch COA with every lot

16-section GHS SDS

Export to 120+ countries

DG-compliant packing

About Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine)

Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) (CAS 89270-25-7) is a metabolite or degradation product of Cyclosporin offered by Vaqora Chemicals. Formula C62H111N11O13, molecular weight 1218.6 g/mol. It is also known as Cyclosporin AM 9 or (4-Hydroxy-N-methyl-L-leucine)cyclosporine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Cyclosporin, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Cyclosporin

View every impurity, metabolite and intermediate we list for Cyclosporin.

Cyclosporin impurities

Specifications & identifiers

Chemical identifiers
Product name	Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine)
Catalogue No.	VQ-036478
CAS Number	89270-25-7
IUPAC name	(3S,6S,9S,12R,15S,18S,21S,24S,30S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-9-(2-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,18,24-tris(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Molecular formula	C₆₂H₁₁₁N₁₁O₁₃
Molecular weight	1218.6 g/mol
Exact mass	1217.8363
Grade	Reference Standard
HSN code	38229090
InChIKey	ODPRYBDBGFBROY-DTLHCQOUSA-N
SMILES	CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N(C(C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)(C)O)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
PubChem CID	6442653

Physical properties
Physical form	Solid
LogP (XLogP3)	6.1
H-bond donors / acceptors	6 / 13
TPSA	299 Å²
Synonyms	Cyclosporin AM 9, (4-Hydroxy-N-methyl-L-leucine)cyclosporine, [.gamma.-Hydroxy-MeLeu]9-CsA, [.gamma.-Hydroxy-MeLeu]9-Ciclosporin, [.gamma.-Hydroxy-MeLeu]9-Cyclosporin

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine)?

The CAS Registry Number of Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) is 89270-25-7. It is also known as Cyclosporin AM 9, (4-Hydroxy-N-methyl-L-leucine)cyclosporine, [.gamma.-Hydroxy-MeLeu]9-CsA.

What is the molecular formula and molecular weight of Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine)?

Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) has the molecular formula C62H111N11O13 and a molecular weight of 1218.6 g/mol.

What is Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) used for?

Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) is supplied as a characterised reference material related to Cyclosporin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) can I order?

We supply Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine)?

Yes. Every lot of Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) be shipped internationally?

Yes. We export Cyclosporin A, 3-(4-hydroxy-N-methyl-L-leucine) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.