Dabigatran Impurity E

Name: Dabigatran Impurity E
Brand: Vaqora Chemicals
SKU: VQ-029978

About Dabigatran Impurity E

Listed under CAS 1456889-80-7, Dabigatran Impurity E is an impurity of Dabigatran available from Vaqora Chemicals. Formula C20H22N4O3, molecular weight 366.4 g/mol. Systematically, it is named ethyl 3-[(1,2-dimethylbenzimidazole-5-carbonyl)-pyridin-2-ylamino]propanoate. It is also known as Dabigatran Etexilate Impurity N.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Dabigatran to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dabigatran

View every impurity, metabolite and intermediate we list for Dabigatran.

Dabigatran impurities

Specifications & identifiers

Chemical identifiers
Product name	Dabigatran Impurity E
Catalogue No.	VQ-029978
CAS Number	1456889-80-7
IUPAC name	ethyl 3-[(1,2-dimethylbenzimidazole-5-carbonyl)-pyridin-2-ylamino]propanoate
Molecular formula	C₂₀H₂₂N₄O₃
Molecular weight	366.4 g/mol
Exact mass	366.1692
Grade	Reference Standard
HSN code	38229090
InChIKey	WYUWBSPFQWDSIN-UHFFFAOYSA-N
SMILES	CCOC(=O)CCN(C1=CC=CC=N1)C(=O)C2=CC3=C(C=C2)N(C(=N3)C)C
PubChem CID	86298229

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	0 / 5
TPSA	77.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dabigatran Impurity E?

The CAS Registry Number of Dabigatran Impurity E is 1456889-80-7. It is also known as ethyl 3-(1,2-dimethyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate, Dabigatran Etexilate Impurity N, ethyl 3-[(1,2-dimethylbenzimidazole-5-carbonyl)-(2-pyridyl)amino]propanoate.

What is the molecular formula and molecular weight of Dabigatran Impurity E?

Dabigatran Impurity E has the molecular formula C20H22N4O3 and a molecular weight of 366.4 g/mol. Its IUPAC name is ethyl 3-[(1,2-dimethylbenzimidazole-5-carbonyl)-pyridin-2-ylamino]propanoate.

What is Dabigatran Impurity E used for?

Dabigatran Impurity E is supplied as a characterised reference material related to Dabigatran. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dabigatran Impurity E can I order?

We supply Dabigatran Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dabigatran Impurity E?

Yes. Every lot of Dabigatran Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dabigatran Impurity E be shipped internationally?

Yes. We export Dabigatran Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.