Dapagliflozin Methoxy Impurity

Name: Dapagliflozin Methoxy Impurity
Brand: Vaqora Chemicals
SKU: VQ-004724

About Dapagliflozin Methoxy Impurity

Listed under CAS 714269-57-5, Dapagliflozin Methoxy Impurity is an impurity of Dapagliflozin available from Vaqora Chemicals with a typical assay of 93%. Formula C22H27ClO7, molecular weight 438.9 g/mol. Systematically, it is named (2S,3R,4S,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)-2-methoxyoxane-3,4,5-triol. Common synonyms include Dapagliflozin Methoxy Pyranose Impurity and Methoxy Dapagliflozin.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Dapagliflozin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Dapagliflozin Methoxy Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dapagliflozin

View every impurity, metabolite and intermediate we list for Dapagliflozin.

Dapagliflozin impurities

Specifications & identifiers

Chemical identifiers
Product name	Dapagliflozin Methoxy Impurity
Catalogue No.	VQ-004724
CAS Number	714269-57-5
IUPAC name	(2S,3R,4S,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)-2-methoxyoxane-3,4,5-triol
Molecular formula	C₂₂H₂₇ClO₇
Molecular weight	438.9 g/mol
Exact mass	438.1445
Grade	Reference Standard
Purity / assay	93%
HSN code	38229090
InChIKey	GKTWLVVOULBRDU-BDHVOXNPSA-N
SMILES	CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@]3([C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)OC)Cl
PubChem CID	24807437

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	4 / 7
TPSA	109 Å²
Synonyms	Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside, Dapagliflozin Methoxy Pyranose Impurity, Methoxy Dapagliflozin, 1alpha-Methoxy Dapagliflozin, 1alpha-Methyl Dapagliflozin, Methyl 1-C-(4-chloro-3-((4-ethoxyphenyl)methyl)phenyl)-alpha-D-glucopyranoside, Methyl 1-C-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-alpha-D-glucopyranoside, Dapagliflozin Impurity 16, alpha-D-Glucopyranoside, methyl 1-C-(4-chloro-3-((4-ethoxyphenyl)methyl)phenyl)-, alpha-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, 1a-Methyl Dapagliflozin, N-Propargyl-1(R)-aminoindan methanesulfonate

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P261, P264, P264 + P265, P270, P272, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dapagliflozin Methoxy Impurity?

The CAS Registry Number of Dapagliflozin Methoxy Impurity is 714269-57-5. It is also known as Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside, Dapagliflozin Methoxy Pyranose Impurity, Methoxy Dapagliflozin.

What is the molecular formula and molecular weight of Dapagliflozin Methoxy Impurity?

Dapagliflozin Methoxy Impurity has the molecular formula C22H27ClO7 and a molecular weight of 438.9 g/mol. Its IUPAC name is (2S,3R,4S,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)-2-methoxyoxane-3,4,5-triol.

What is Dapagliflozin Methoxy Impurity used for?

Dapagliflozin Methoxy Impurity is supplied as a characterised reference material related to Dapagliflozin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dapagliflozin Methoxy Impurity can I order?

We supply Dapagliflozin Methoxy Impurity in Reference Standard (93%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dapagliflozin Methoxy Impurity?

Yes. Every lot of Dapagliflozin Methoxy Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dapagliflozin Methoxy Impurity be shipped internationally?

Yes. Dapagliflozin Methoxy Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.