Demethoxy Curcumin

Name: Demethoxy Curcumin
Brand: Vaqora Chemicals
SKU: VQ-025097

About Demethoxy Curcumin

Vaqora Chemicals supplies Demethoxy Curcumin, an impurity of Curcumin registered under CAS number 22608-11-3. Formula C20H18O5, molecular weight 338.4 g/mol. The IUPAC name is (1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione. It is also known as (2E)-Demethoxy Curcumin or curcumin II.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Curcumin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Demethoxy Curcumin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Curcumin

View every impurity, metabolite and intermediate we list for Curcumin.

Curcumin impurities

Specifications & identifiers

Chemical identifiers
Product name	Demethoxy Curcumin
Catalogue No.	VQ-025097
CAS Number	22608-11-3
IUPAC name	(1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
Molecular formula	C₂₀H₁₈O₅
Molecular weight	338.4 g/mol
Exact mass	338.1154
Grade	Reference Standard
HSN code	38229090
InChIKey	HJTVQHVGMGKONQ-LUZURFALSA-N
SMILES	COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC=C(C=C2)O)O
PubChem CID	5469424

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	2 / 5
TPSA	83.8 Å²
Synonyms	(2E)-Demethoxy Curcumin, curcumin II, desmethoxycurcumin, 4-Hydroxycinnamoyl(feroyl)methane, Feruloyl-P-hydroxycinnnamoylmethane, monodemethoxycurcumin, (E/Z)-Demethoxycurcumin, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione, 1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, p-Hydroxycinnamoyl-feruloylmethane

Safety & hazard information (GHS)

Environmental hazard

Signal word: Warning

Hazard statements

H400Very toxic to aquatic life

Precautionary statements: P273, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Demethoxy Curcumin?

The CAS Registry Number of Demethoxy Curcumin is 22608-11-3. It is also known as (2E)-Demethoxy Curcumin, curcumin II, desmethoxycurcumin.

What is the molecular formula and molecular weight of Demethoxy Curcumin?

Demethoxy Curcumin has the molecular formula C20H18O5 and a molecular weight of 338.4 g/mol. Its IUPAC name is (1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione.

What is Demethoxy Curcumin used for?

Demethoxy Curcumin is supplied as a characterised reference material related to Curcumin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Demethoxy Curcumin can I order?

We supply Demethoxy Curcumin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Demethoxy Curcumin?

Yes. Every lot of Demethoxy Curcumin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Demethoxy Curcumin be shipped internationally?

Yes. Demethoxy Curcumin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.