Desacetyl N,O-didesmethyl Diltiazem

Name: Desacetyl N,O-didesmethyl Diltiazem
Brand: Vaqora Chemicals
SKU: VQ-025326

About Desacetyl N,O-didesmethyl Diltiazem

Listed under CAS 86408-42-6, Desacetyl N,O-didesmethyl Diltiazem is a metabolite or degradation product of Diltiazem available from Vaqora Chemicals. The compound has the formula C18H20N2O3S, corresponding to a molecular weight of 344.4 g/mol. Systematically, it is named (2S,3S)-3-hydroxy-2-(4-hydroxyphenyl)-5-[2-(methylamino)ethyl]-2,3-dihydro-1,5-benzothiazepin-4-one. It is also known as Deacetyl-N,O-didemethyldiltiazem or N,O-Didemethyldeacetyldiltiazem.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Diltiazem, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Desacetyl N,O-didesmethyl Diltiazem in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Diltiazem

View every impurity, metabolite and intermediate we list for Diltiazem.

Diltiazem impurities

Specifications & identifiers

Chemical identifiers
Product name	Desacetyl N,O-didesmethyl Diltiazem
Catalogue No.	VQ-025326
CAS Number	86408-42-6
IUPAC name	(2S,3S)-3-hydroxy-2-(4-hydroxyphenyl)-5-[2-(methylamino)ethyl]-2,3-dihydro-1,5-benzothiazepin-4-one
Molecular formula	C₁₈H₂₀N₂O₃S
Molecular weight	344.4 g/mol
Exact mass	344.1195
Grade	Reference Standard
HSN code	38229090
InChIKey	ZTRZZXJIQHVVGS-SJORKVTESA-N
SMILES	CNCCN1C2=CC=CC=C2S[C@H]([C@H](C1=O)O)C3=CC=C(C=C3)O
PubChem CID	10472681

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	3 / 5
TPSA	98.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Desacetyl N,O-didesmethyl Diltiazem?

The CAS Registry Number of Desacetyl N,O-didesmethyl Diltiazem is 86408-42-6. It is also known as Deacetyl-N,O-didemethyldiltiazem, N,O-Didemethyldeacetyldiltiazem, o-Desmethyldeacetylnordiltiazem.

What is the molecular formula and molecular weight of Desacetyl N,O-didesmethyl Diltiazem?

Desacetyl N,O-didesmethyl Diltiazem has the molecular formula C18H20N2O3S and a molecular weight of 344.4 g/mol. Its IUPAC name is (2S,3S)-3-hydroxy-2-(4-hydroxyphenyl)-5-[2-(methylamino)ethyl]-2,3-dihydro-1,5-benzothiazepin-4-one.

What is Desacetyl N,O-didesmethyl Diltiazem used for?

Desacetyl N,O-didesmethyl Diltiazem is supplied as a characterised reference material related to Diltiazem. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Desacetyl N,O-didesmethyl Diltiazem can I order?

We supply Desacetyl N,O-didesmethyl Diltiazem in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Desacetyl N,O-didesmethyl Diltiazem?

Yes. Every lot of Desacetyl N,O-didesmethyl Diltiazem is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Desacetyl N,O-didesmethyl Diltiazem be shipped internationally?

Yes. We export Desacetyl N,O-didesmethyl Diltiazem worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.