Desloratadine

Name: Desloratadine
Brand: Vaqora Chemicals
SKU: VQ-004765

About Desloratadine

Listed under CAS 100643-71-8, Desloratadine is an impurity of Desloratadine available from Vaqora Chemicals. Its molecular formula is C19H19ClN2 and its molecular weight is 310.8 g/mol. Its systematic (IUPAC) name is 13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene. Alternative names: Aerius and Allex.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Desloratadine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Desloratadine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Desloratadine

View every impurity, metabolite and intermediate we list for Desloratadine.

Desloratadine impurities

Specifications & identifiers

Chemical identifiers
Product name	Desloratadine
Catalogue No.	VQ-004765
CAS Number	100643-71-8
IUPAC name	13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
Molecular formula	C₁₉H₁₉ClN₂
Molecular weight	310.8 g/mol
Exact mass	310.1237
Grade	Reference Standard
HSN code	38229090
InChIKey	JAUOIFJMECXRGI-UHFFFAOYSA-N
SMILES	C1CC2=C(C=CC(=C2)Cl)C(=C3CCNCC3)C4=C1C=CC=N4
PubChem CID	124087

Physical properties
Physical form	Solid
LogP (XLogP3)	4.5
H-bond donors / acceptors	1 / 2
TPSA	24.9 Å²
Synonyms	8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, Aerius, Allex, Azomyr, Clarinex, Descarboethoxyloratadine, Neoclarityn, Opulis, Desloratidine, Denosin, 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, Desloratadine Actavis

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H318Causes serious eye damage
H361Suspected of damaging fertility or the unborn child
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P264 + P265, P270, P272, P273, P280, P301 + P317, P302 + P352, P305 + P354 + P338, P317, P318, P321, P330, P333 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Desloratadine?

The CAS Registry Number of Desloratadine is 100643-71-8. It is also known as 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, Aerius, Allex.

What is the molecular formula and molecular weight of Desloratadine?

Desloratadine has the molecular formula C19H19ClN2 and a molecular weight of 310.8 g/mol. Its IUPAC name is 13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene.

What is Desloratadine used for?

Desloratadine is supplied as a characterised reference material related to Desloratadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Desloratadine can I order?

We supply Desloratadine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Desloratadine?

Yes. Every lot of Desloratadine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Desloratadine be shipped internationally?

Yes. Desloratadine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.