Diethyl (Hydroxymethyl) Phosphonate

Name: Diethyl (Hydroxymethyl) Phosphonate
Brand: Vaqora Chemicals
SKU: VQ-042422

About Diethyl (Hydroxymethyl) Phosphonate

Diethyl (Hydroxymethyl) Phosphonate (CAS 3084-40-0) is a metabolite or degradation product of Tenofovir offered by Vaqora Chemicals. Its molecular formula is C5H13O4P and its molecular weight is 168.13 g/mol. The IUPAC name is diethoxyphosphorylmethanol. Common synonyms include Diethy (hydroxymethyl) phosphonate and Diethyl phosphonomethanol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Tenofovir, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Diethyl (Hydroxymethyl) Phosphonate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tenofovir

View every impurity, metabolite and intermediate we list for Tenofovir.

Tenofovir impurities

Specifications & identifiers

Chemical identifiers
Product name	Diethyl (Hydroxymethyl) Phosphonate
Catalogue No.	VQ-042422
CAS Number	3084-40-0
IUPAC name	diethoxyphosphorylmethanol
Molecular formula	C₅H₁₃O₄P
Molecular weight	168.13 g/mol
Exact mass	168.0551
Grade	Reference Standard
HSN code	38229090
InChIKey	RWIGWWBLTJLKMK-UHFFFAOYSA-N
SMILES	CCOP(=O)(CO)OCC
PubChem CID	76513

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	1 / 4
TPSA	55.8 Å²
Synonyms	Diethy (hydroxymethyl) phosphonate, Diethyl phosphonomethanol, Phosphonic acid, (hydroxymethyl)-, diethyl ester, (Hydroxymethyl)phosphonic acid, diethyl ester, Phosphonic acid, P-(hydroxymethyl)-, diethyl ester, diethyl P-(hydroxymethyl)phosphonate, (Hydroxymethyl)phosphonic Acid Diethyl Ester, diethoxyphosphoryl-methanol, diethyl hydroxymethanephosphonate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diethyl (Hydroxymethyl) Phosphonate?

The CAS Registry Number of Diethyl (Hydroxymethyl) Phosphonate is 3084-40-0. It is also known as Diethy (hydroxymethyl) phosphonate, Diethyl phosphonomethanol, Phosphonic acid, (hydroxymethyl)-, diethyl ester.

What is the molecular formula and molecular weight of Diethyl (Hydroxymethyl) Phosphonate?

Diethyl (Hydroxymethyl) Phosphonate has the molecular formula C5H13O4P and a molecular weight of 168.13 g/mol. Its IUPAC name is diethoxyphosphorylmethanol.

What is Diethyl (Hydroxymethyl) Phosphonate used for?

Diethyl (Hydroxymethyl) Phosphonate is supplied as a characterised reference material related to Tenofovir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diethyl (Hydroxymethyl) Phosphonate can I order?

We supply Diethyl (Hydroxymethyl) Phosphonate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diethyl (Hydroxymethyl) Phosphonate?

Yes. Every lot of Diethyl (Hydroxymethyl) Phosphonate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diethyl (Hydroxymethyl) Phosphonate be shipped internationally?

Yes. Diethyl (Hydroxymethyl) Phosphonate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.