Diethyl (tosyloxy)methylphosphonate

Name: Diethyl (tosyloxy)methylphosphonate
Brand: Vaqora Chemicals
SKU: VQ-013367

About Diethyl (tosyloxy)methylphosphonate

Diethyl (tosyloxy)methylphosphonate is a process intermediate or related compound of Tenofovir carrying the CAS registry number 31618-90-3. The compound has the formula C12H19O6PS, corresponding to a molecular weight of 322.32 g/mol. Its systematic (IUPAC) name is diethoxyphosphorylmethyl 4-methylbenzenesulfonate. Alternative names: Diethoxyphosphorylmethyl tosylate and Diethyl p-tosyloxymethylphosphonate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Process chemists and analysts use it when developing synthetic routes to Tenofovir, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Diethyl (tosyloxy)methylphosphonate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Tenofovir

View every impurity, metabolite and intermediate we list for Tenofovir.

Tenofovir impurities

Specifications & identifiers

Chemical identifiers
Product name	Diethyl (tosyloxy)methylphosphonate
Catalogue No.	VQ-013367
CAS Number	31618-90-3
IUPAC name	diethoxyphosphorylmethyl 4-methylbenzenesulfonate
Molecular formula	C₁₂H₁₉O₆PS
Molecular weight	322.32 g/mol
Exact mass	322.064
Grade	Reference Standard
InChIKey	UOEFFQWLRUBDME-UHFFFAOYSA-N
SMILES	CCOP(=O)(COS(=O)(=O)C1=CC=C(C=C1)C)OCC
PubChem CID	4193599

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	0 / 6
TPSA	87.3 Å²
Synonyms	Diethyl P-[[[(4-methylphenyl)sulfonyl]oxy]methyl]phosphonate, (Diethoxyphosphoryl)methyl 4-methylbenzenesulfonate, 4-Methylbenzenesulfonic acid (diethoxyphosphoryl)methyl ester, Diethoxyphosphorylmethyl tosylate, Diethyl [[(p-toluenesulfonyl)oxy]methyl]phosphonate, Diethyl [[[(4-tolyl)sulfonyl]oxy]methyl]phosphonate, Diethyl p-tosyloxymethylphosphonate, Tosyloxymethyl diethyl phosphonate, [[[(4-Tolyl)sulfonyl]oxy]methyl]phosphonic acid diethyl ester, Diethyl P-((((4-methylphenyl)sulfonyl)oxy)methyl)phosphonate, Diethyl 4-toluenesulfonyloxymethylphosphonate, Diethyl p-Toluenesulfonyloxymethylphosphonate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 31618-90-3

Diethyl (p-toluenesulfonyloxymethyl)phosphonate, 98%

CAS: 31618-90-3
Formula: C₁₂H₁₉O₆PS
MW: 322.32 g/mol

VQ-011421

Frequently asked questions

What is the CAS number of Diethyl (tosyloxy)methylphosphonate?

The CAS Registry Number of Diethyl (tosyloxy)methylphosphonate is 31618-90-3. It is also known as Diethyl P-[[[(4-methylphenyl)sulfonyl]oxy]methyl]phosphonate, (Diethoxyphosphoryl)methyl 4-methylbenzenesulfonate, 4-Methylbenzenesulfonic acid (diethoxyphosphoryl)methyl ester.

What is the molecular formula and molecular weight of Diethyl (tosyloxy)methylphosphonate?

Diethyl (tosyloxy)methylphosphonate has the molecular formula C12H19O6PS and a molecular weight of 322.32 g/mol. Its IUPAC name is diethoxyphosphorylmethyl 4-methylbenzenesulfonate.

What is Diethyl (tosyloxy)methylphosphonate used for?

Diethyl (tosyloxy)methylphosphonate is supplied as a characterised reference material related to Tenofovir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diethyl (tosyloxy)methylphosphonate can I order?

We supply Diethyl (tosyloxy)methylphosphonate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diethyl (tosyloxy)methylphosphonate?

Yes. Every lot of Diethyl (tosyloxy)methylphosphonate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diethyl (tosyloxy)methylphosphonate be shipped internationally?

Yes. We export Diethyl (tosyloxy)methylphosphonate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.