Diflorasone

Name: Diflorasone
Brand: Vaqora Chemicals
SKU: VQ-025311

About Diflorasone

Diflorasone is an impurity of Diflorasone Diacetate carrying the CAS registry number 2557-49-5. Formula C22H28F2O5, molecular weight 410.5 g/mol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Diflorasone Diacetate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Diflorasone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Diflorasone Diacetate

View every impurity, metabolite and intermediate we list for Diflorasone Diacetate.

Diflorasone Diacetate impurities

Specifications & identifiers

Chemical identifiers
Product name	Diflorasone
Catalogue No.	VQ-025311
CAS Number	2557-49-5
IUPAC name	(6S,8S,9R,10S,11S,13S,14S,16S,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₂₈F₂O₅
Molecular weight	410.5 g/mol
Exact mass	410.1905
Grade	Reference Standard
HSN code	38229090
InChIKey	WXURHACBFYSXBI-XHIJKXOTSA-N
SMILES	C[C@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C)F
PubChem CID	71415

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	3 / 7
TPSA	94.8 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H312Harmful in contact with skin
H319Causes serious eye irritation
H361Suspected of damaging fertility or the unborn child
H371May cause damage to organs

Precautionary statements: P203, P260, P264, P264 + P265, P270, P280, P302 + P352, P305 + P351 + P338, P308 + P316, P317, P318, P321, P337 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diflorasone?

The CAS Registry Number of Diflorasone is 2557-49-5. It is also known as 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione.

What is the molecular formula and molecular weight of Diflorasone?

Diflorasone has the molecular formula C22H28F2O5 and a molecular weight of 410.5 g/mol.

What is Diflorasone used for?

Diflorasone is supplied as a characterised reference material related to Diflorasone Diacetate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diflorasone can I order?

We supply Diflorasone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diflorasone?

Yes. Every lot of Diflorasone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diflorasone be shipped internationally?

Yes. Diflorasone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.