Dihydroartemisinin

Name: Dihydroartemisinin
Brand: Vaqora Chemicals
SKU: VQ-020831

About Dihydroartemisinin

Dihydroartemisinin is an impurity of Artemether carrying the CAS registry number 71939-50-9. The compound has the formula C15H24O5, corresponding to a molecular weight of 284.35 g/mol. The IUPAC name is (1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol. It is also known as Dihydroartemisinin Intermediate or Artenimol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Artemether to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Dihydroartemisinin is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Artemether

View every impurity, metabolite and intermediate we list for Artemether.

Artemether impurities

Specifications & identifiers

Chemical identifiers
Product name	Dihydroartemisinin
Catalogue No.	VQ-020831
CAS Number	71939-50-9
IUPAC name	(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol
Molecular formula	C₁₅H₂₄O₅
Molecular weight	284.35 g/mol
Exact mass	284.1624
Grade	Reference Standard
HSN code	38229090
InChIKey	BJDCWCLMFKKGEE-ISOSDAIHSA-N
SMILES	C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)O)C
PubChem CID	3000518

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 5
TPSA	57.2 Å²
Synonyms	Dihydroartemisinin Intermediate, Artenimol, Cotexin, Alaxin, Cotecxin, Dihydroartemisinine, Salaxin, Santecxin, Di-hydroqinghaosu, GNF-PF-5634, beta-Dihydroartemisinin, quinghaosu, dihydro-

Safety & hazard information (GHS)

Flammable

Environmental hazard

Signal word: Danger

Hazard statements

H242Heating may cause a fire
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P210, P234, P235, P240, P273, P280, P370 + P378, P391, P403, P410, P411, P420, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dihydroartemisinin?

The CAS Registry Number of Dihydroartemisinin is 71939-50-9. It is also known as Dihydroartemisinin Intermediate, Artenimol, Cotexin.

What is the molecular formula and molecular weight of Dihydroartemisinin?

Dihydroartemisinin has the molecular formula C15H24O5 and a molecular weight of 284.35 g/mol. Its IUPAC name is (1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol.

What is Dihydroartemisinin used for?

Dihydroartemisinin is supplied as a characterised reference material related to Artemether. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dihydroartemisinin can I order?

We supply Dihydroartemisinin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dihydroartemisinin?

Yes. Every lot of Dihydroartemisinin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dihydroartemisinin be shipped internationally?

Yes. Dihydroartemisinin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.