Dihydrocinchonidine

Name: Dihydrocinchonidine
Brand: Vaqora Chemicals
SKU: VQ-041805

About Dihydrocinchonidine

Dihydrocinchonidine (CAS 485-64-3) is an impurity of Quinine offered by Vaqora Chemicals. Formula C19H24N2O, molecular weight 296.4 g/mol. Its systematic (IUPAC) name is (R)-[(2S,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol. It is also known as Cinchamidine or Hydrocinchonidine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Quinine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Dihydrocinchonidine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Quinine

View every impurity, metabolite and intermediate we list for Quinine.

Quinine impurities

Specifications & identifiers

Chemical identifiers
Product name	Dihydrocinchonidine
Catalogue No.	VQ-041805
CAS Number	485-64-3
IUPAC name	(R)-[(2S,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
Molecular formula	C₁₉H₂₄N₂O
Molecular weight	296.4 g/mol
Exact mass	296.1889
Grade	Reference Standard
HSN code	38229090
InChIKey	WFJNHVWTKZUUTR-KODHJQJWSA-N
SMILES	CC[C@H]1CN2CC[C@H]1C[C@H]2[C@@H](C3=CC=NC4=CC=CC=C34)O
PubChem CID	6914728

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	1 / 3
TPSA	36.4 Å²
Synonyms	Cinchamidine, Hydrocinchonidine, (8alpha,9R)-10,11-Dihydrocinchonan-9-ol, (R)-((1S,2S,4S,5R)-5-Ethylquinuclidin-2-yl)(quinolin-4-yl)methanol, (3R,8S,9R)-10,11-Dihydrocinchonidine, GNF-Pf-1324, (8, A,9R)-10,11-dihydro-Cinchonan-9-ol, (9R)-8alpha-10,11-Dihydrocinchonan-9-ol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction

Precautionary statements: P261, P264, P270, P272, P280, P301 + P317, P302 + P352, P321, P330, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dihydrocinchonidine?

The CAS Registry Number of Dihydrocinchonidine is 485-64-3. It is also known as Cinchamidine, Hydrocinchonidine, (8alpha,9R)-10,11-Dihydrocinchonan-9-ol.

What is the molecular formula and molecular weight of Dihydrocinchonidine?

Dihydrocinchonidine has the molecular formula C19H24N2O and a molecular weight of 296.4 g/mol. Its IUPAC name is (R)-[(2S,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol.

What is Dihydrocinchonidine used for?

Dihydrocinchonidine is supplied as a characterised reference material related to Quinine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dihydrocinchonidine can I order?

We supply Dihydrocinchonidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dihydrocinchonidine?

Yes. Every lot of Dihydrocinchonidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dihydrocinchonidine be shipped internationally?

Yes. Dihydrocinchonidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.