Dimethyl D-glutamate Hydrochloride

Name: Dimethyl D-glutamate Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-048893

About Dimethyl D-glutamate Hydrochloride

Vaqora Chemicals supplies Dimethyl D-glutamate Hydrochloride, a process intermediate or related compound of Linagliptin registered under CAS number 27025-25-8. Formula C7H14ClNO4, molecular weight 211.64 g/mol. It is also known as H-D-Glu(OMe)-OMe.HCl or D-Glutamic Acid Dimethyl Ester Hydrochloride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Linagliptin, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Dimethyl D-glutamate Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Linagliptin

View every impurity, metabolite and intermediate we list for Linagliptin.

Linagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Dimethyl D-glutamate Hydrochloride
Catalogue No.	VQ-048893
CAS Number	27025-25-8
IUPAC name	dimethyl (2R)-2-aminopentanedioate;hydrochloride
Molecular formula	C₇H₁₄ClNO₄
Molecular weight	211.64 g/mol
Exact mass	211.0611
InChIKey	MFUPLHQOVIUESQ-NUBCRITNSA-N
SMILES	COC(=O)CC[C@H](C(=O)OC)N.Cl
PubChem CID	12917567

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 5
TPSA	78.6 Å²
Synonyms	D-Glutamic acid, dimethyl ester, hydrochloride, Glutamic acid, dimethyl ester, hydrochloride, D-, D-Glutamic acid, 1,5-dimethyl ester, hydrochloride (1:1), H-D-Glu(OMe)-OMe.HCl, (R)-Dimethyl 2-aminopentanedioate hydrochloride, D-Glutamic Acid 1,5-Dimethyl Ester Hydrochloride, D-Glutamic Acid Dimethyl Ester Hydrochloride, H-D-Glu(ome)-ome hydrochloride, D-Glutamic acid dimethyl ester HCl, Dimethyl D-glutamate HCl, H-D-Glu(OMe)-OMe inverted exclamation mark currencyHCl, dimethyl (R)-glutamate hydrochloride

Safety & hazard information (GHS)

Explosive

Harmful / irritant

Signal word: Danger

Hazard statements

H240Heating may cause an explosion
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P210, P234, P235, P240, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P370 + P372 + P380 + P373, P403, P403 + P233

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dimethyl D-glutamate Hydrochloride?

The CAS Registry Number of Dimethyl D-glutamate Hydrochloride is 27025-25-8. It is also known as D-Glutamic acid, dimethyl ester, hydrochloride, Glutamic acid, dimethyl ester, hydrochloride, D-, D-Glutamic acid, 1,5-dimethyl ester, hydrochloride (1:1).

What is the molecular formula and molecular weight of Dimethyl D-glutamate Hydrochloride?

Dimethyl D-glutamate Hydrochloride has the molecular formula C7H14ClNO4 and a molecular weight of 211.64 g/mol.

What is Dimethyl D-glutamate Hydrochloride used for?

Dimethyl D-glutamate Hydrochloride is supplied as a characterised reference material related to Linagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dimethyl D-glutamate Hydrochloride can I order?

We supply Dimethyl D-glutamate Hydrochloride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dimethyl D-glutamate Hydrochloride?

Yes. Every lot of Dimethyl D-glutamate Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dimethyl D-glutamate Hydrochloride be shipped internationally?

Yes. Dimethyl D-glutamate Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.