Dinitroso Ethambutol

Name: Dinitroso Ethambutol
Brand: Vaqora Chemicals
SKU: VQ-037120

About Dinitroso Ethambutol

Dinitroso Ethambutol (CAS 2792161-95-4) is a nitrosamine impurity of Ethambutol offered by Vaqora Chemicals. With the molecular formula C10H22N4O4, it has a molar mass of 262.31 g/mol. Systematically, it is named N-[(2S)-1-hydroxybutan-2-yl]-N-[2-[[(2S)-1-hydroxybutan-2-yl]-nitrosoamino]ethyl]nitrous amide. It is also known as (S,S)Dinitroso Ethambutol or N,N'-Dinitrosoethambutol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Dinitroso Ethambutol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Ethambutol

View every impurity, metabolite and intermediate we list for Ethambutol.

Ethambutol impurities

Specifications & identifiers

Chemical identifiers
Product name	Dinitroso Ethambutol
Catalogue No.	VQ-037120
CAS Number	2792161-95-4
IUPAC name	N-[(2S)-1-hydroxybutan-2-yl]-N-[2-[[(2S)-1-hydroxybutan-2-yl]-nitrosoamino]ethyl]nitrous amide
Molecular formula	C₁₀H₂₂N₄O₄
Molecular weight	262.31 g/mol
Exact mass	262.1641
Grade	Reference Standard
HSN code	38229090
InChIKey	GEIAKCPGVIYGOY-UWVGGRQHSA-N
SMILES	CC[C@@H](CO)N(CCN([C@@H](CC)CO)N=O)N=O
PubChem CID	121489243

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	2 / 8
TPSA	106 Å²
Synonyms	(2S)-2-[(2-{[(2S)-1-hydroxybutan-2-yl](nitroso)amino}ethyl)(nitroso)amino]butan-1-ol, (2S)-2-((2-(((2S)-1-hydroxybutan-2-yl)(nitroso)amino)ethyl)(nitroso)amino)butan-1-ol, (S,S)Dinitroso Ethambutol, N,N'-Dinitrosoethambutol, d-N,N'-Bisnitroso-N,N'-bis(1-hydroxymethylpropyl)ethylenediamine, 2,2'-(Ethylenebis(nitrosoimino))bisbutanol, d-N,N'-(1-Hydroxymethylpropyl)ethylenedinitrosamine, d-N,N'-(1-Idrossimetil propil)-etilendinitrosamina

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dinitroso Ethambutol?

The CAS Registry Number of Dinitroso Ethambutol is 2792161-95-4. It is also known as (2S)-2-[(2-{[(2S)-1-hydroxybutan-2-yl](nitroso)amino}ethyl)(nitroso)amino]butan-1-ol, (2S)-2-((2-(((2S)-1-hydroxybutan-2-yl)(nitroso)amino)ethyl)(nitroso)amino)butan-1-ol, (S,S)Dinitroso Ethambutol.

What is the molecular formula and molecular weight of Dinitroso Ethambutol?

Dinitroso Ethambutol has the molecular formula C10H22N4O4 and a molecular weight of 262.31 g/mol. Its IUPAC name is N-[(2S)-1-hydroxybutan-2-yl]-N-[2-[[(2S)-1-hydroxybutan-2-yl]-nitrosoamino]ethyl]nitrous amide.

What is Dinitroso Ethambutol used for?

Dinitroso Ethambutol is supplied as a characterised reference material related to Ethambutol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dinitroso Ethambutol can I order?

We supply Dinitroso Ethambutol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dinitroso Ethambutol?

Yes. Every lot of Dinitroso Ethambutol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dinitroso Ethambutol be shipped internationally?

Yes. Dinitroso Ethambutol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.