Diphenhydramine Citrate

Name: Diphenhydramine Citrate
Brand: Vaqora Chemicals
SKU: VQ-036731

About Diphenhydramine Citrate

Vaqora Chemicals supplies Diphenhydramine Citrate, a high-purity reference standard of Diphenhydramine registered under CAS number 88637-37-0. The compound has the formula C23H29NO8, corresponding to a molecular weight of 447.5 g/mol.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Diphenhydramine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Diphenhydramine

View every impurity, metabolite and intermediate we list for Diphenhydramine.

Diphenhydramine impurities

Specifications & identifiers

Chemical identifiers
Product name	Diphenhydramine Citrate
Catalogue No.	VQ-036731
CAS Number	88637-37-0
IUPAC name	2-benzhydryloxy-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid
Molecular formula	C₂₃H₂₉NO₈
Molecular weight	447.5 g/mol
Exact mass	447.1893
Grade	Reference Standard
HSN code	38229090
InChIKey	SPCKHVPPRJWQRZ-UHFFFAOYSA-N
SMILES	CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
PubChem CID	174697

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 9
TPSA	145 Å²
Synonyms	2-(Diphenylmethoxy)-N,N-dimethylethylamine citrate (1:1), 2-(Benzhydryloxy)-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate, Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1), 2-(Benzhydryloxy)-N,N-dimethylethanamine2-hydroxypropane-1,2,3-tricarboxylate, 2-benzhydryloxy-N,N-dimethylethanamine,2-hydroxypropane-1,2,3-tricarboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H317May cause an allergic skin reaction
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P264, P270, P271, P272, P280, P284, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diphenhydramine Citrate?

The CAS Registry Number of Diphenhydramine Citrate is 88637-37-0. It is also known as 2-(Diphenylmethoxy)-N,N-dimethylethylamine citrate (1:1), 2-(Benzhydryloxy)-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate, Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1).

What is the molecular formula and molecular weight of Diphenhydramine Citrate?

Diphenhydramine Citrate has the molecular formula C23H29NO8 and a molecular weight of 447.5 g/mol.

What is Diphenhydramine Citrate used for?

Diphenhydramine Citrate is supplied as a characterised reference material related to Diphenhydramine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diphenhydramine Citrate can I order?

We supply Diphenhydramine Citrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diphenhydramine Citrate?

Yes. Every lot of Diphenhydramine Citrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diphenhydramine Citrate be shipped internationally?

Yes. Diphenhydramine Citrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.