Docetaxel Trihydrate

Name: Docetaxel Trihydrate
Brand: Vaqora Chemicals
SKU: VQ-025353

About Docetaxel Trihydrate

Listed under CAS 148408-66-6, Docetaxel Trihydrate is a high-purity reference standard of Docetaxel available from Vaqora Chemicals. Formula C43H59NO17, molecular weight 861.9 g/mol. Alternative names: Docetaxel hydrate and Docetaxel hydrate (JP18).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 7 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Docetaxel, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Docetaxel Trihydrate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Docetaxel

View every impurity, metabolite and intermediate we list for Docetaxel.

Docetaxel impurities

Specifications & identifiers

Chemical identifiers
Product name	Docetaxel Trihydrate
Catalogue No.	VQ-025353
CAS Number	148408-66-6
IUPAC name	[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12-trihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate;trihydrate
Molecular formula	C₄₃H₅₉NO₁₇
Molecular weight	861.9 g/mol
Exact mass	861.3783
Grade	Reference Standard
HSN code	38229090
InChIKey	XCDIRYDKECHIPE-QHEQPUDQSA-N
SMILES	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O.O.O.O
PubChem CID	148123

Physical properties
Physical form	Solid
H-bond donors / acceptors	8 / 17
TPSA	227 Å²
Synonyms	Docetaxel hydrate, N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol trihydrate, N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel trihydrate, Docetaxel hydrate (JP18), Docetaxel trihydrate - Bio-X trade mark

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H319Causes serious eye irritation
H341Suspected of causing genetic defects
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P263, P264, P264 + P265, P270, P273, P280, P305 + P351 + P338, P318, P319, P337 + P317, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Docetaxel Trihydrate?

The CAS Registry Number of Docetaxel Trihydrate is 148408-66-6. It is also known as Docetaxel hydrate, N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol trihydrate, N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel trihydrate.

What is the molecular formula and molecular weight of Docetaxel Trihydrate?

Docetaxel Trihydrate has the molecular formula C43H59NO17 and a molecular weight of 861.9 g/mol.

What is Docetaxel Trihydrate used for?

Docetaxel Trihydrate is supplied as a characterised reference material related to Docetaxel. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Docetaxel Trihydrate can I order?

We supply Docetaxel Trihydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Docetaxel Trihydrate?

Yes. Every lot of Docetaxel Trihydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Docetaxel Trihydrate be shipped internationally?

Yes. Docetaxel Trihydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.