Dodecamethylcyclohexasiloxane

Name: Dodecamethylcyclohexasiloxane
Brand: Vaqora Chemicals
SKU: VQ-029953

About Dodecamethylcyclohexasiloxane

Dodecamethylcyclohexasiloxane is an impurity of Cyclomethicone carrying the CAS registry number 540-97-6. With the molecular formula C12H36O6Si6, it has a molar mass of 444.92 g/mol. The IUPAC name is 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane. It is also known as Cyclomethicone 6 or Cyclohexasiloxane, dodecamethyl-.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Cyclomethicone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Dodecamethylcyclohexasiloxane in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cyclomethicone

View every impurity, metabolite and intermediate we list for Cyclomethicone.

Cyclomethicone impurities

Specifications & identifiers

Chemical identifiers
Product name	Dodecamethylcyclohexasiloxane
Catalogue No.	VQ-029953
CAS Number	540-97-6
IUPAC name	2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
Molecular formula	C₁₂H₃₆O₆Si₆
Molecular weight	444.92 g/mol
Exact mass	444.1127
Grade	Reference Standard
HSN code	38229090
InChIKey	IUMSDRXLFWAGNT-UHFFFAOYSA-N
SMILES	C[Si]1(O[Si](O[Si](O[Si](O[Si](O[Si](O1)(C)C)(C)C)(C)C)(C)C)(C)C)C
PubChem CID	10911

Physical properties
Physical form	Solid
H-bond donors / acceptors	0 / 6
TPSA	55.4 Å²
Synonyms	Cyclomethicone 6, Cyclohexasiloxane, dodecamethyl-, Cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane, Dodecamethylhexacyclosiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane #, cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl, Cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-, 2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane, AldrichCPR, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexa

Safety & hazard information (GHS)

Hazard statements

H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P273, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dodecamethylcyclohexasiloxane?

The CAS Registry Number of Dodecamethylcyclohexasiloxane is 540-97-6. It is also known as Cyclomethicone 6, Cyclohexasiloxane, dodecamethyl-, Cyclohexasiloxane.

What is the molecular formula and molecular weight of Dodecamethylcyclohexasiloxane?

Dodecamethylcyclohexasiloxane has the molecular formula C12H36O6Si6 and a molecular weight of 444.92 g/mol. Its IUPAC name is 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane.

What is Dodecamethylcyclohexasiloxane used for?

Dodecamethylcyclohexasiloxane is supplied as a characterised reference material related to Cyclomethicone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dodecamethylcyclohexasiloxane can I order?

We supply Dodecamethylcyclohexasiloxane in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dodecamethylcyclohexasiloxane?

Yes. Every lot of Dodecamethylcyclohexasiloxane is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dodecamethylcyclohexasiloxane be shipped internationally?

Yes. We export Dodecamethylcyclohexasiloxane worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.