Doravirine Pyridone Impurity (DOR-VI)

Name: Doravirine Pyridone Impurity (DOR-VI)
Brand: Vaqora Chemicals
SKU: VQ-045310

About Doravirine Pyridone Impurity (DOR-VI)

Listed under CAS 1155846-86-8, Doravirine Pyridone Impurity (DOR-VI) is an impurity of Doravirine available from Vaqora Chemicals. Formula C13H6ClF3N2O2, molecular weight 314.64 g/mol. Its systematic (IUPAC) name is 3-chloro-5-[[2-oxo-4-(trifluoromethyl)-1H-pyridin-3-yl]oxy]benzonitrile. Alternative names: Doravirine Pyridinone Impurity and Doravirine metabolite M11.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Doravirine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Doravirine

View every impurity, metabolite and intermediate we list for Doravirine.

Doravirine impurities

Specifications & identifiers

Chemical identifiers
Product name	Doravirine Pyridone Impurity (DOR-VI)
Catalogue No.	VQ-045310
CAS Number	1155846-86-8
IUPAC name	3-chloro-5-[[2-oxo-4-(trifluoromethyl)-1H-pyridin-3-yl]oxy]benzonitrile
Molecular formula	C₁₃H₆ClF₃N₂O₂
Molecular weight	314.64 g/mol
Exact mass	314.007
Grade	Reference Standard
HSN code	38229090
InChIKey	HWTORHRJFMRBLG-UHFFFAOYSA-N
SMILES	C1=CNC(=O)C(=C1C(F)(F)F)OC2=CC(=CC(=C2)C#N)Cl
PubChem CID	58460048

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	1 / 6
TPSA	62.1 Å²
Synonyms	Doravirine Pyridinone Impurity, 3-chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile, Doravirine metabolite M11, 3-chloro-5-{[2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]oxy}benzonitrile, Benzonitrile, 3-chloro-5-[[1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]-, 3-Chloro-5-((2-oxo-4-(trifluoromethyl)-1H-pyridin-3-yl)oxy)benzonitrile, 3-Chloro-5-((1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl)oxy)benzonitrile, Benzonitrile, 3-chloro-5-((1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl)oxy)-, 3-Chloro-5-[[1,2-dihydro-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]benzonitrile, 3-chloro-5-(2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yloxy)benzonitrile, MK -1439 intermediate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Doravirine Pyridone Impurity (DOR-VI)?

The CAS Registry Number of Doravirine Pyridone Impurity (DOR-VI) is 1155846-86-8. It is also known as Doravirine Pyridinone Impurity, 3-chloro-5-((2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile, Doravirine metabolite M11.

What is the molecular formula and molecular weight of Doravirine Pyridone Impurity (DOR-VI)?

Doravirine Pyridone Impurity (DOR-VI) has the molecular formula C13H6ClF3N2O2 and a molecular weight of 314.64 g/mol. Its IUPAC name is 3-chloro-5-[[2-oxo-4-(trifluoromethyl)-1H-pyridin-3-yl]oxy]benzonitrile.

What is Doravirine Pyridone Impurity (DOR-VI) used for?

Doravirine Pyridone Impurity (DOR-VI) is supplied as a characterised reference material related to Doravirine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Doravirine Pyridone Impurity (DOR-VI) can I order?

We supply Doravirine Pyridone Impurity (DOR-VI) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Doravirine Pyridone Impurity (DOR-VI)?

Yes. Every lot of Doravirine Pyridone Impurity (DOR-VI) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Doravirine Pyridone Impurity (DOR-VI) be shipped internationally?

Yes. We export Doravirine Pyridone Impurity (DOR-VI) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.