Doxazosin

Name: Doxazosin
Brand: Vaqora Chemicals
SKU: VQ-030300

About Doxazosin

Doxazosin (CAS 74191-85-8) is a high-purity reference standard of Doxazosin offered by Vaqora Chemicals. The compound has the formula C23H25N5O5, corresponding to a molecular weight of 451.5 g/mol. The IUPAC name is [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone. Alternative names: Doxazosine and ratio Doxazosin.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Doxazosin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Doxazosin

View every impurity, metabolite and intermediate we list for Doxazosin.

Doxazosin impurities

Specifications & identifiers

Chemical identifiers
Product name	Doxazosin
Catalogue No.	VQ-030300
CAS Number	74191-85-8
IUPAC name	[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
Molecular formula	C₂₃H₂₅N₅O₅
Molecular weight	451.5 g/mol
Exact mass	451.1856
Grade	Reference Standard
HSN code	38229090
InChIKey	RUZYUOTYCVRMRZ-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC
PubChem CID	3157

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 9
TPSA	112 Å²
Synonyms	Doxazosine, 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin, ratio Doxazosin, ratio-Doxazosin, Doxazosin Wolff, Novo Doxazosin, Apo Doxazosin, Gen Doxazosin, Doxa Puren, MTW Doxazosin, Neo, Carduran, Doxazosin ratiopharm

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P260, P264, P270, P273, P280, P301 + P317, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P319, P321, P330, P363, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Doxazosin?

The CAS Registry Number of Doxazosin is 74191-85-8. It is also known as Doxazosine, 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin, ratio Doxazosin.

What is the molecular formula and molecular weight of Doxazosin?

Doxazosin has the molecular formula C23H25N5O5 and a molecular weight of 451.5 g/mol. Its IUPAC name is [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone.

What is Doxazosin used for?

Doxazosin is supplied as a characterised reference material related to Doxazosin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Doxazosin can I order?

We supply Doxazosin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Doxazosin?

Yes. Every lot of Doxazosin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Doxazosin be shipped internationally?

Yes. Doxazosin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.