Doxylamine

Name: Doxylamine
Brand: Vaqora Chemicals
SKU: VQ-036823

About Doxylamine

Listed under CAS 469-21-6, Doxylamine is a high-purity reference standard of Doxylamine available from Vaqora Chemicals. Formula C17H22N2O, molecular weight 270.37 g/mol. Systematically, it is named N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine. It is also known as Doxylamine for system suitability or 2-Dimethylaminoethoxyphenylmethyl-2-picoline.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Doxylamine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Doxylamine

View every impurity, metabolite and intermediate we list for Doxylamine.

Doxylamine impurities

Specifications & identifiers

Chemical identifiers
Product name	Doxylamine
Catalogue No.	VQ-036823
CAS Number	469-21-6
IUPAC name	N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine
Molecular formula	C₁₇H₂₂N₂O
Molecular weight	270.37 g/mol
Exact mass	270.1732
Grade	Reference Standard
HSN code	38229090
InChIKey	HCFDWZZGGLSKEP-UHFFFAOYSA-N
SMILES	CC(C1=CC=CC=C1)(C2=CC=CC=N2)OCCN(C)C
PubChem CID	3162

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	0 / 3
TPSA	25.4 Å²
Synonyms	Doxylamine for system suitability, 2-Dimethylaminoethoxyphenylmethyl-2-picoline, N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine, Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether, 2-(alpha-(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine, dimethyl({2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethyl})amine, Ethanamine, N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)-, Pyridine, 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-, Ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-, dimethyl((2-(1-phenyl-1-(pyridin-2-yl)ethoxy)ethyl))amine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Doxylamine?

The CAS Registry Number of Doxylamine is 469-21-6. It is also known as Doxylamine for system suitability, 2-Dimethylaminoethoxyphenylmethyl-2-picoline, N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine.

What is the molecular formula and molecular weight of Doxylamine?

Doxylamine has the molecular formula C17H22N2O and a molecular weight of 270.37 g/mol. Its IUPAC name is N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine.

What is Doxylamine used for?

Doxylamine is supplied as a characterised reference material related to Doxylamine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Doxylamine can I order?

We supply Doxylamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Doxylamine?

Yes. Every lot of Doxylamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Doxylamine be shipped internationally?

Yes. Doxylamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.