Duloxetine Impurity 5

Name: Duloxetine Impurity 5
Brand: Vaqora Chemicals
SKU: VQ-004827

About Duloxetine Impurity 5

Duloxetine Impurity 5 (CAS 645411-16-1) is an impurity of Duloxetine offered by Vaqora Chemicals. Formula C8H12ClNOS, molecular weight 205.71 g/mol. Systematically, it is named 3-(methylamino)-1-thiophen-2-ylpropan-1-one. Hydrochloride. Common synonyms include Duloxetine salt.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Duloxetine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Duloxetine Impurity 5 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	Duloxetine Impurity 5
Catalogue No.	VQ-004827
CAS Number	645411-16-1
Other CAS	667465-15-8
IUPAC name	3-(methylamino)-1-thiophen-2-ylpropan-1-one;hydrochloride
Molecular formula	C₈H₁₂ClNOS
Molecular weight	205.71 g/mol
Exact mass	205.0328
Grade	Reference Standard
HSN code	38229090
InChIKey	XVOVLSVOAJYLHZ-UHFFFAOYSA-N
SMILES	CNCCC(=O)C1=CC=CS1.Cl
PubChem CID	10035872

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	57.3 Å²
Synonyms	3-(N-Methylamino)-1-(2-thienyl)-1-propanone hydrochloride, 3-(Methylamino)-1-(2-thienyl)propan-1-one hydrochloride, 3-(Methylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride, 1-Propanone, 3-(methylamino)-1-(2-thienyl)-, hydrochloride (1:1), 1-Propanone, 3-(methylamino)-1-(2-thienyl)-, hydrochloride, Duloxetine salt, 3-(Methylamino)-1-(thiophen-2-yl)propan-1-onehydrochloride, 3-(Methylamino)-1-(2-thienyl)-1-propanone Hydrochloride, 1-Propanone,3-(methylamino)-1-(2-thienyl)-,hydrochloride(1:1), 3-(methylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride645411-16-1, 3-(Methylamino)-1-(thiophen-2-yl)propan-1-one--hydrogen chloride (1/1)

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P260, P264, P270, P273, P280, P301 + P317, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P330, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Duloxetine Impurity 5?

The CAS Registry Number of Duloxetine Impurity 5 is 645411-16-1. It is also known as 3-(N-Methylamino)-1-(2-thienyl)-1-propanone hydrochloride, 3-(Methylamino)-1-(2-thienyl)propan-1-one hydrochloride, 3-(Methylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride.

What is the molecular formula and molecular weight of Duloxetine Impurity 5?

Duloxetine Impurity 5 has the molecular formula C8H12ClNOS and a molecular weight of 205.71 g/mol.

What is Duloxetine Impurity 5 used for?

Duloxetine Impurity 5 is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Duloxetine Impurity 5 can I order?

We supply Duloxetine Impurity 5 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Duloxetine Impurity 5?

Yes. Every lot of Duloxetine Impurity 5 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Duloxetine Impurity 5 be shipped internationally?

Yes. Duloxetine Impurity 5 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.