(E)-Doxepin

Name: (E)-Doxepin
Brand: Vaqora Chemicals
SKU: VQ-036812

About (E)-Doxepin

Vaqora Chemicals supplies (E)-Doxepin, a high-purity reference standard of Doxepin registered under CAS number 3607-34-9. Its molecular formula is C19H21NO and its molecular weight is 279.4 g/mol. Its systematic (IUPAC) name is (3E)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine. Common synonyms include trans-doxepin and Doxepin, (E)-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Doxepin, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (E)-Doxepin in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Doxepin

View every impurity, metabolite and intermediate we list for Doxepin.

Doxepin impurities

Specifications & identifiers

Chemical identifiers
Product name	(E)-Doxepin
Catalogue No.	VQ-036812
CAS Number	3607-34-9
IUPAC name	(3E)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine
Molecular formula	C₁₉H₂₁NO
Molecular weight	279.4 g/mol
Exact mass	279.1623
Grade	Reference Standard
HSN code	38229090
InChIKey	ODQWQRRAPPTVAG-GZTJUZNOSA-N
SMILES	CN(C)CC/C=C/1\C2=CC=CC=C2COC3=CC=CC=C31
PubChem CID	667477

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	0 / 2
TPSA	12.5 Å²
Synonyms	trans-doxepin, Doxepin, (E)-, Doxepine hydrochloride, 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz(b,e)oxipin, MF 10, (3e)-3-(Dibenzo[b,E]oxepin-11(6h)-Ylidene)-N,N-Dimethylpropan-1-Amine, [11C]doxepin, 3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, [11C]-doxepin, 11-(3-(Dimethylamino)propylidene)-6H-dibenz(b,e)oxepine, (E)-3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, 5EH

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P263, P264, P270, P273, P280, P301 + P316, P318, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (E)-Doxepin?

The CAS Registry Number of (E)-Doxepin is 3607-34-9. It is also known as trans-doxepin, Doxepin, (E)-, Doxepine hydrochloride.

What is the molecular formula and molecular weight of (E)-Doxepin?

(E)-Doxepin has the molecular formula C19H21NO and a molecular weight of 279.4 g/mol. Its IUPAC name is (3E)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine.

What is (E)-Doxepin used for?

(E)-Doxepin is supplied as a characterised reference material related to Doxepin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (E)-Doxepin can I order?

We supply (E)-Doxepin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (E)-Doxepin?

Yes. Every lot of (E)-Doxepin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (E)-Doxepin be shipped internationally?

Yes. (E)-Doxepin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.