Edaravone Impurity 4

Name: Edaravone Impurity 4
Brand: Vaqora Chemicals
SKU: VQ-004837

About Edaravone Impurity 4

Listed under CAS 7477-67-0, Edaravone Impurity 4 is an impurity of Edaravone available from Vaqora Chemicals. The compound has the formula C20H18N4O2, corresponding to a molecular weight of 346.4 g/mol. The IUPAC name is 5-methyl-4-(3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-yl)-2-phenyl-4H-pyrazol-3-one. It is also known as Bispyrazolone or 4,4'-Bis(1-phenyl-3-methyl-5-pyrazolone).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Edaravone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Edaravone Impurity 4 is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Edaravone

View every impurity, metabolite and intermediate we list for Edaravone.

Edaravone impurities

Specifications & identifiers

Chemical identifiers
Product name	Edaravone Impurity 4
Catalogue No.	VQ-004837
CAS Number	7477-67-0
IUPAC name	5-methyl-4-(3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-yl)-2-phenyl-4H-pyrazol-3-one
Molecular formula	C₂₀H₁₈N₄O₂
Molecular weight	346.4 g/mol
Exact mass	346.143
Grade	Reference Standard
HSN code	38229090
InChIKey	FORCWSNQDMPPOC-UHFFFAOYSA-N
SMILES	CC1=NN(C(=O)C1C2C(=NN(C2=O)C3=CC=CC=C3)C)C4=CC=CC=C4
PubChem CID	95807

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	0 / 4
TPSA	65.3 Å²
Synonyms	Bispyrazolone, 2,2',4,4'-Tetrahydro-5,5'-dimethyl-2,2'-diphenyl-[4,4'-Bi-3H-pyrazole]-3,3'-dione, 3,3'-Dimethyl-1,1'-diphenyl-[4,4'-bi-2-pyrazoline]-5,5'-dione, 4,4'-Bis(1-phenyl-3-methyl-5-pyrazolone), [4,4'-Bi-3H-pyrazole]-3,3'-dione, 2,2',4,4'-tetrahydro-5,5'-dimethyl-2,2'-diphenyl-, (4,4'-Bi-2-pyrazoline)-5,5'-dione, 3,3'-dimethyl-1,1'-diphenyl-, 3,3'-Dimethyl-1,1'-diphenyl-4,4'-bi-5-pyrazolone, (4,4'-Bi-3H-pyrazole)-3,3'-dione, 2,2',4,4'-tetrahydro-5,5'-dimethyl-2,2'-diphenyl-, 3,3'Dimethyl1,1'diphenyl4,4'bi5pyrazolone, (4,4'Bi2pyrazoline)5,5'dione, 3,3'dimethyl1,1'diphenyl, (4,4'Bi3Hpyrazole)3,3'dione, 2,2',4,4'tetrahydro5,5'dimethyl2,2'diphenyl, 3,3'-Dimethyl-1,1'-diphenyl-1H,1'H-[4,4'-bipyrazole]-5,5'(4H,4'H)-dione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements: P261, P272, P280, P302 + P352, P321, P333 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 7477-67-0

Bispyrazolone, ≥95.00%

CAS: 7477-67-0
Formula: C₂₀H₁₈N₄O₂
MW: 346.4 g/mol

VQ-046872

AR

Bispyrazolone, GR

CAS: 7477-67-0
Formula: C₂₀H₁₈N₄O₂
MW: 346.4 g/mol

VQ-000820

Frequently asked questions

What is the CAS number of Edaravone Impurity 4?

The CAS Registry Number of Edaravone Impurity 4 is 7477-67-0. It is also known as Bispyrazolone, 2,2',4,4'-Tetrahydro-5,5'-dimethyl-2,2'-diphenyl-[4,4'-Bi-3H-pyrazole]-3,3'-dione, 3,3'-Dimethyl-1,1'-diphenyl-[4,4'-bi-2-pyrazoline]-5,5'-dione.

What is the molecular formula and molecular weight of Edaravone Impurity 4?

Edaravone Impurity 4 has the molecular formula C20H18N4O2 and a molecular weight of 346.4 g/mol. Its IUPAC name is 5-methyl-4-(3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-yl)-2-phenyl-4H-pyrazol-3-one.

What is Edaravone Impurity 4 used for?

Edaravone Impurity 4 is supplied as a characterised reference material related to Edaravone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Edaravone Impurity 4 can I order?

We supply Edaravone Impurity 4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Edaravone Impurity 4?

Yes. Every lot of Edaravone Impurity 4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Edaravone Impurity 4 be shipped internationally?

Yes. Edaravone Impurity 4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.