Efavirenz

Name: Efavirenz
Brand: Vaqora Chemicals
SKU: VQ-030386

About Efavirenz

Listed under CAS 154598-52-4, Efavirenz is a high-purity reference standard of Efavirenz available from Vaqora Chemicals. The compound has the formula C14H9ClF3NO2, corresponding to a molecular weight of 315.67 g/mol. Systematically, it is named (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one. Alternative names: Efavirenz Beta Form and Stocrin.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Efavirenz, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Efavirenz is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Efavirenz

View every impurity, metabolite and intermediate we list for Efavirenz.

Efavirenz impurities

Specifications & identifiers

Chemical identifiers
Product name	Efavirenz
Catalogue No.	VQ-030386
CAS Number	154598-52-4
IUPAC name	(4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
Molecular formula	C₁₄H₉ClF₃NO₂
Molecular weight	315.67 g/mol
Exact mass	315.0274
Grade	Reference Standard
HSN code	38229090
InChIKey	XPOQHMRABVBWPR-ZDUSSCGKSA-N
SMILES	C1CC1C#C[C@]2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F
PubChem CID	64139

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	1 / 5
TPSA	38.3 Å²
Synonyms	Efavirenz Beta Form, Stocrin, DMP-266, Efavirenz teva, (S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one, (s)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one, (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo(d)(1,3)oxazin-2-one, efavirenz, (S)-, Sustiva 600, (S)-Efavirenz, (Rac)-Efavirenz

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P264 + P265, P270, P273, P280, P301 + P317, P305 + P351 + P338, P318, P319, P330, P337 + P317, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Efavirenz?

The CAS Registry Number of Efavirenz is 154598-52-4. It is also known as Efavirenz Beta Form, Stocrin, DMP-266.

What is the molecular formula and molecular weight of Efavirenz?

Efavirenz has the molecular formula C14H9ClF3NO2 and a molecular weight of 315.67 g/mol. Its IUPAC name is (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one.

What is Efavirenz used for?

Efavirenz is supplied as a characterised reference material related to Efavirenz. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Efavirenz can I order?

We supply Efavirenz in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Efavirenz?

Yes. Every lot of Efavirenz is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Efavirenz be shipped internationally?

Yes. Efavirenz is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.