Emtricitabine 5-Fluorouracil Analog

Name: Emtricitabine 5-Fluorouracil Analog
Brand: Vaqora Chemicals
SKU: VQ-013390

About Emtricitabine 5-Fluorouracil Analog

Emtricitabine 5-Fluorouracil Analog (CAS 145986-11-4) is a process intermediate or related compound of Emtricitabine offered by Vaqora Chemicals. With the molecular formula C8H9FN2O4S, it has a molar mass of 248.23 g/mol. Its systematic (IUPAC) name is 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione. It is also known as Emtricitabine 4-Hydroxy Analog or Oxathiolan 5FU-beta.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Emtricitabine, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Emtricitabine 5-Fluorouracil Analog is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Emtricitabine

View every impurity, metabolite and intermediate we list for Emtricitabine.

Emtricitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	Emtricitabine 5-Fluorouracil Analog
Catalogue No.	VQ-013390
CAS Number	145986-11-4
IUPAC name	5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione
Molecular formula	C₈H₉FN₂O₄S
Molecular weight	248.23 g/mol
Exact mass	248.0267
Grade	Reference Standard
HSN code	2933
InChIKey	KOGYOPLNKQJQFM-NTSWFWBYSA-N
SMILES	C1[C@H](O[C@H](S1)CO)N2C=C(C(=O)NC2=O)F
PubChem CID	126768

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.6
H-bond donors / acceptors	2 / 6
TPSA	104 Å²
Synonyms	5-Fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolane-5-yl]uracil, cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione, (2R-cis)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione, 5-Fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione, Emtricitabine 4-Hydroxy Analog, 1-[(2R,5S)-2-(Hydroxymethyl-1,3-oxathiolan-5-yl]-5-fluoropyrimidine-2,4(1H,3H)-dione, 1-((2R,5S)-2-(Hydroxymethyl-1,3-oxathiolan-5-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione, Oxathiolan 5FU-beta, Emtricitabine 5-fluorouracil, 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, 5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidine-2,4(1H,3H)-dione, Cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Emtricitabine 5-Fluorouracil Analog?

The CAS Registry Number of Emtricitabine 5-Fluorouracil Analog is 145986-11-4. It is also known as 5-Fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolane-5-yl]uracil, cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione, (2R-cis)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione.

What is the molecular formula and molecular weight of Emtricitabine 5-Fluorouracil Analog?

Emtricitabine 5-Fluorouracil Analog has the molecular formula C8H9FN2O4S and a molecular weight of 248.23 g/mol. Its IUPAC name is 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4-dione.

What is Emtricitabine 5-Fluorouracil Analog used for?

Emtricitabine 5-Fluorouracil Analog is supplied as a characterised reference material related to Emtricitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Emtricitabine 5-Fluorouracil Analog can I order?

We supply Emtricitabine 5-Fluorouracil Analog in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Emtricitabine 5-Fluorouracil Analog?

Yes. Every lot of Emtricitabine 5-Fluorouracil Analog is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Emtricitabine 5-Fluorouracil Analog be shipped internationally?

Yes. Emtricitabine 5-Fluorouracil Analog is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.