Ensifentrine

Name: Ensifentrine
Brand: Vaqora Chemicals
SKU: VQ-030483

About Ensifentrine

Ensifentrine is a high-purity reference standard of Ensifentrine carrying the CAS registry number 1884461-72-6. Formula C26H31N5O4, molecular weight 477.6 g/mol. Its systematic (IUPAC) name is 2-[9,10-dimethoxy-4-oxo-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[6,1-a]isoquinolin-3-yl]ethylurea. It is also known as RPL-554 or (E/Z)-Ensifentrine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Ensifentrine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Ensifentrine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ensifentrine

View every impurity, metabolite and intermediate we list for Ensifentrine.

Ensifentrine impurities

Specifications & identifiers

Chemical identifiers
Product name	Ensifentrine
Catalogue No.	VQ-030483
CAS Number	1884461-72-6
IUPAC name	2-[9,10-dimethoxy-4-oxo-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[6,1-a]isoquinolin-3-yl]ethylurea
Molecular formula	C₂₆H₃₁N₅O₄
Molecular weight	477.6 g/mol
Exact mass	477.2376
Grade	Reference Standard
HSN code	38229090
InChIKey	CSOBIBXVIYAXFM-UHFFFAOYSA-N
SMILES	CC1=CC(=C(C(=C1)C)N=C2C=C3C4=CC(=C(C=C4CCN3C(=O)N2CCNC(=O)N)OC)OC)C
PubChem CID	9934746

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 5
TPSA	109 Å²
Synonyms	RPL-554, (E/Z)-Ensifentrine, VMX-554, EX-A6633, (E)-Ensifentrine, VMX 554

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H335May cause respiratory irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P261, P264, P271, P280, P302 + P352, P304 + P340, P319, P321, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ensifentrine?

The CAS Registry Number of Ensifentrine is 1884461-72-6. It is also known as RPL-554, (E/Z)-Ensifentrine, VMX-554.

What is the molecular formula and molecular weight of Ensifentrine?

Ensifentrine has the molecular formula C26H31N5O4 and a molecular weight of 477.6 g/mol. Its IUPAC name is 2-[9,10-dimethoxy-4-oxo-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[6,1-a]isoquinolin-3-yl]ethylurea.

What is Ensifentrine used for?

Ensifentrine is supplied as a characterised reference material related to Ensifentrine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ensifentrine can I order?

We supply Ensifentrine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ensifentrine?

Yes. Every lot of Ensifentrine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ensifentrine be shipped internationally?

Yes. Ensifentrine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.