Erlotinib Hydroxy Metabolite

Name: Erlotinib Hydroxy Metabolite
Brand: Vaqora Chemicals
SKU: VQ-048254

About Erlotinib Hydroxy Metabolite

Erlotinib Hydroxy Metabolite (CAS 882420-22-6) is a metabolite or degradation product of Erlotinib offered by Vaqora Chemicals. Formula C22H23N3O5, molecular weight 409.4 g/mol. The IUPAC name is 4-[[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amino]-2-ethynylphenol. Alternative names: Erlotinib metabolite M16 and 4'-Hydroxy erlotinib.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Erlotinib, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Erlotinib Hydroxy Metabolite is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Erlotinib

View every impurity, metabolite and intermediate we list for Erlotinib.

Erlotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Erlotinib Hydroxy Metabolite
Catalogue No.	VQ-048254
CAS Number	882420-22-6
IUPAC name	4-[[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amino]-2-ethynylphenol
Molecular formula	C₂₂H₂₃N₃O₅
Molecular weight	409.4 g/mol
Exact mass	409.1638
Grade	Reference Standard
HSN code	38229090
InChIKey	NEEHJGWAKAIBAR-UHFFFAOYSA-N
SMILES	COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)C#C)OCCOC
PubChem CID	74963268

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	2 / 8
TPSA	95 Å²
Synonyms	Erlotinib metabolite M16, 4-((6,7-Bis(2-methoxyethoxy)quinazolin-4-yl)amino)-2-ethynyl-phenol, Phenol, 4-((6,7-bis(2-methoxyethoxy)-4-quinazolinyl)amino)-2-ethynyl-, 4'-Hydroxy erlotinib, Erlotinib Impurity 6, 4-((6,7-bis(2-methoxyethoxy)quinazolin-4-yl)amino)-2-ethynylphenol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Erlotinib Hydroxy Metabolite?

The CAS Registry Number of Erlotinib Hydroxy Metabolite is 882420-22-6. It is also known as Erlotinib metabolite M16, 4-((6,7-Bis(2-methoxyethoxy)quinazolin-4-yl)amino)-2-ethynyl-phenol, Phenol, 4-((6,7-bis(2-methoxyethoxy)-4-quinazolinyl)amino)-2-ethynyl-.

What is the molecular formula and molecular weight of Erlotinib Hydroxy Metabolite?

Erlotinib Hydroxy Metabolite has the molecular formula C22H23N3O5 and a molecular weight of 409.4 g/mol. Its IUPAC name is 4-[[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amino]-2-ethynylphenol.

What is Erlotinib Hydroxy Metabolite used for?

Erlotinib Hydroxy Metabolite is supplied as a characterised reference material related to Erlotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Erlotinib Hydroxy Metabolite can I order?

We supply Erlotinib Hydroxy Metabolite in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Erlotinib Hydroxy Metabolite?

Yes. Every lot of Erlotinib Hydroxy Metabolite is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Erlotinib Hydroxy Metabolite be shipped internationally?

Yes. We export Erlotinib Hydroxy Metabolite worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.