Erlotinib Lactam Impurity

Name: Erlotinib Lactam Impurity
Brand: Vaqora Chemicals
SKU: VQ-004924

About Erlotinib Lactam Impurity

Erlotinib Lactam Impurity (CAS 179688-29-0) is an impurity of Erlotinib offered by Vaqora Chemicals. The compound has the formula C14H18N2O5, corresponding to a molecular weight of 294.3 g/mol. Its systematic (IUPAC) name is 6,7-bis(2-methoxyethoxy)-3H-quinazolin-4-one. It is also known as 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone or 6,7-Bis(2-methoxyethoxy)quinazolin-4(3H)-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Erlotinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Erlotinib Lactam Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Erlotinib

View every impurity, metabolite and intermediate we list for Erlotinib.

Erlotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Erlotinib Lactam Impurity
Catalogue No.	VQ-004924
CAS Number	179688-29-0
IUPAC name	6,7-bis(2-methoxyethoxy)-3H-quinazolin-4-one
Molecular formula	C₁₄H₁₈N₂O₅
Molecular weight	294.3 g/mol
Exact mass	294.1216
Grade	Reference Standard
HSN code	38229090
InChIKey	PMQWTUWLIGJTQD-UHFFFAOYSA-N
SMILES	COCCOC1=C(C=C2C(=C1)C(=O)NC=N2)OCCOC
PubChem CID	135409305

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	1 / 6
TPSA	78.4 Å²
Synonyms	6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone, 6,7-Bis(2-methoxyethoxy)-quinazoline-4(3H)-one, 6,7-Bis(2-methoxyethoxy)quinazolin-4(3H)-one, 6,7-Di(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 4(3H)-Quinazolinone, 6,7-bis(2-methoxyethoxy)-, 6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone, 6,7-Bis(2-Methoxyethoxy)Quinazolin-4(1H)-One, 6,7-bis-(2-Methoxyethoxy)-quinazolin-4(3h)-one, Erlotinib Impurity 7, 6,7-bis-(2-methoxyethoxy)-4(3H)quinazolinone, 6,7-bis(2-methoxyethoxy)-1H-quinazolin-4-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Erlotinib Lactam Impurity?

The CAS Registry Number of Erlotinib Lactam Impurity is 179688-29-0. It is also known as 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone, 6,7-Bis(2-methoxyethoxy)-quinazoline-4(3H)-one.

What is the molecular formula and molecular weight of Erlotinib Lactam Impurity?

Erlotinib Lactam Impurity has the molecular formula C14H18N2O5 and a molecular weight of 294.3 g/mol. Its IUPAC name is 6,7-bis(2-methoxyethoxy)-3H-quinazolin-4-one.

What is Erlotinib Lactam Impurity used for?

Erlotinib Lactam Impurity is supplied as a characterised reference material related to Erlotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Erlotinib Lactam Impurity can I order?

We supply Erlotinib Lactam Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Erlotinib Lactam Impurity?

Yes. Every lot of Erlotinib Lactam Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Erlotinib Lactam Impurity be shipped internationally?

Yes. Erlotinib Lactam Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.